Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing (Q41653940)

6 October 2017

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing (English)

1 reference

6 October 2017

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4

1 reference

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12 June 2020

author name string

Marie-Cécile Didiot

1

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12 June 2020

Lauren M Hall

2

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12 June 2020

Andrew H Coles

3

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12 June 2020

Bruno Mdc Godinho

5

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12 June 2020

Kathryn Chase

6

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12 June 2020

Ellen Sapp

7

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12 June 2020

Socheata Ly

8

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12 June 2020

Julia F Alterman

9

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12 June 2020

Matthew R Hassler

10

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12 June 2020

Dimas Echeverria

11

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12 June 2020

Lakshmi Raj

12

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12 June 2020

David V Morrissey

13

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12 June 2020

Marian DiFiglia

14

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12 June 2020

Neil Aronin

15

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12 June 2020

Anastasia Khvorova

16

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12 June 2020

publication date

9 August 2016

1 reference

6 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27506293%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

24

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12 June 2020

issue

10

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12 June 2020

page(s)

1836-1847

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27506293%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5112038/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain

6 June 2018

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Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

6 June 2018

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Exosomes as a potential tool for a specific delivery of functional molecules

6 June 2018

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6 June 2018

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Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity

6 June 2018

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The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

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6 June 2018

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Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth

6 June 2018

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Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

6 June 2018

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6 June 2018

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RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

6 June 2018

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Loss of normal huntingtin function: new developments in Huntington's disease research

6 June 2018

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Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

6 June 2018

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A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

6 June 2018

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

6 June 2018

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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

6 June 2018

1 reference

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Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5112038

Safety and efficacy of RNAi therapy for transthyretin amyloidosis

18 August 2018

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Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27506293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2016.126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27506293%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27506293%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference