Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection (Q41857492)

13 October 2017

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection (English)

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13 October 2017

10

Nicolas Chomont

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13 October 2017

1

Lydie Trautmann

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13 October 2017

12

Rafick-Pierre Sekaly

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13 October 2017

Florentin-Martial Mbitikon-Kobo

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13 October 2017

Jean-Philippe Goulet

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13 October 2017

Yoav Peretz

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13 October 2017

Yu Shi

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13 October 2017

Julien Van Grevenynghe

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13 October 2017

Francesco Andrea Procopio

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13 October 2017

Mohamad Rachid Boulassel

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13 October 2017

Jean-Pierre Routy

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13 October 2017

Elias K Haddad

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13 October 2017

language of work or name

English

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publication date

6 September 2012

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13 October 2017

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120

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3466-3477

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describes a project that uses

13 October 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/3743465

based on heuristic

inferred from PubMed Central ID database lookup

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

5 June 2018

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5 June 2018

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

5 June 2018

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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18 August 2018

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18 August 2018

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The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration.

18 August 2018

1 reference

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Low levels of perforin expression in CD8+ T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743465

Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743465

Skewed maturation of memory HIV-specific CD8 T lymphocytes

18 August 2018

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18 August 2018

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Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

18 August 2018

1 reference

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Dynamics of T cell responses in HIV infection

2 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22955926

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2012-04-422550

1 reference

13 October 2017

1 reference

13 October 2017

1 reference