Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins. (Q41863848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19863112%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins (English)

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11 February 2020

5

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11 February 2020

Claus Kristensen

6

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11 February 2020

Pierre De Meyts

10

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11 February 2020

author name string

Waseem Sajid

1

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11 February 2020

Patricia A Holst

2

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11 February 2020

Vladislav V Kiselyov

3

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11 February 2020

Asser S Andersen

4

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11 February 2020

Thomas Kjeldsen

7

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11 February 2020

Jonathan Whittaker

8

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11 February 2020

Shu J Chan

9

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11 February 2020

language of work or name

English

0 references

publication date

1 December 2009

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11 February 2020

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11 February 2020

volume

48

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11 February 2020

issue

47

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11 February 2020

page(s)

11283-11295

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Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change

11 February 2020

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Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding

5 June 2018

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5 June 2018

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Structure of the insulin receptor ectodomain reveals a folded-over conformation

5 June 2018

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Expression of insulin in yeast: the importance of molecular adaptation for secretion and conversion

5 June 2018

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Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site

5 June 2018

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Structure and function of the type 1 insulin-like growth factor receptor.

5 June 2018

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Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

5 June 2018

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5 June 2018

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Negative cooperativity in the insulin-like growth factor-I receptor and a chimeric IGF-I/insulin receptor

5 June 2018

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The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling.

5 June 2018

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Messenger RNA sequence and primary structure of preproinsulin in a primitive vertebrate, the Atlantic hagfish.

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Evolution of the insulin gene superfamily. Sequence of a preproinsulin-like growth factor cDNA from the Atlantic hagfish

5 June 2018

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Receptor Binding and Tyrosine Kinase Activation by Insulin Analogues With Extreme Affinities Studied in Human Hepatoma HepG2 Cells

5 June 2018

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The amino acid sequence of the insulin from a primitive vertebrate, the atlantic hagfish (Myxine glutinosa)

5 June 2018

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5 June 2018

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5 June 2018

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The Insulin Receptor and Insulin of the Atlantic Hagfish: Extraordinary Conservation of Binding Specificity and Negative Cooperativity in the Most Primitive Vertebrate

5 June 2018

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5 June 2018

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5 June 2018

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Evolution of the insulin receptor family and receptor isoform expression in vertebrates.

5 June 2018

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How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

18 August 2018

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Some of my not so favorite things about insulin and insulin-like growth factors in fish.

18 August 2018

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Evolution of insulin-like growth factor (IGF) function: production and characterization of recombinant hagfish IGF.

18 August 2018

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An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule.

18 August 2018

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Characterization of insulin, glucagon, and somatostatin from the river lamprey, Lampetra fluviatilis

18 August 2018

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12 December 2020

A removable spacer peptide in an alpha-factor-leader/insulin precursor fusion protein improves processing and concomitant yield of the insulin precursor in Saccharomyces cerevisiae

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12 December 2020

Alanine scanning mutagenesis of insulin

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12 December 2020

Familial amyloid polyneuropathy related to transthyretin mutation Val30 to Leu in a Japanese family

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12 December 2020

Chiral mutagenesis of insulin. Contribution of the B20-B23 beta-turn to activity and stability

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12 December 2020

Structure and biological activity of hagfish insulin

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12 December 2020

Blood sugar regulation in the hagfish, Myxine glutinosa

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12 December 2020

Insulin vom Schleimfisch(Myxine glutinosa; Cyclostomata)

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12 December 2020

Assay of insulin-like activity by the isolated fat cell method. I. Factors influencing the response to crystalline insulin

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12 December 2020

Characteristics of the human lymphocyte insulin receptor

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12 December 2020

A Simple Free Fat Cell Bioassay for Insulin

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12 December 2020

Degradation, receptor binding affinity, and potency of insulin from the Atlantic hagfish (Myxine glutinosa) determined in isolated rat fat cells

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12 December 2020

Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

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12 December 2020

Synthesis and Biological Activity of Seventeen Analogues of Human Insulin

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12 December 2020

18 Systematic mutational analyses of protein-protein interfaces

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12 December 2020

A model for insulin binding to the insulin receptor

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12 December 2020

Hagfish insulin: the discrepancy between binding affinity and biologic activity

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12 December 2020

Non-parallel evolution of metabolic and growth-promoting functions of insulin

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12 December 2020

Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor alpha subunit

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12 December 2020

Identifiers

DOI

10.1021/BI901269J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19863112%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19863112%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference