Interrelationship between HIV-1 fitness and mutation rate. (Q41888126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23084856%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Interrelationship between HIV-1 fitness and mutation rate (English)

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15 February 2020

1

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15 February 2020

author name string

Richard H Heineman

series ordinal

2

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15 February 2020

Louis M Mansky

series ordinal

3

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15 February 2020

language of work or name

English

0 references

publication date

16 October 2012

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Journal of Molecular Biology

15 February 2020

published in

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15 February 2020

volume

425

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15 February 2020

issue

1

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15 February 2020

page(s)

41-53

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Concomitant lethal mutagenesis of human immunodeficiency virus type 1.

15 February 2020

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

5 June 2018

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Complete genetic linkage can subvert natural selection

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice

5 June 2018

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Human immunodeficiency virus mutagenesis during antiviral therapy: impact of drug-resistant reverse transcriptase and nucleoside and nonnucleoside reverse transcriptase inhibitors on human immunodeficiency virus type 1 mutation frequencies

5 June 2018

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Adaptive value of high mutation rates of RNA viruses: separating causes from consequences

5 June 2018

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Methods to determine HIV-1 ex vivo fitness

5 June 2018

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The cost of replication fidelity in an RNA virus

5 June 2018

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Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression

5 June 2018

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KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis

5 June 2018

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5 June 2018

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5 June 2018

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Viral error catastrophe by mutagenic nucleosides

5 June 2018

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Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

5 June 2018

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5 June 2018

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A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.

5 June 2018

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Enrichment and elimination of mutY mutators in Escherichia coli populations

5 June 2018

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Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies

5 June 2018

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A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis

5 June 2018

1 reference

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RNA virus error catastrophe: direct molecular test by using ribavirin

5 June 2018

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The evolution of mutation rates: separating causes from consequences

5 June 2018

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3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.

5 June 2018

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The rate of adaptation in asexuals

5 June 2018

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The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness

5 June 2018

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5 June 2018

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5 June 2018

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HIV-1 evolution under pressure of protease inhibitors: climbing the stairs of viral fitness

5 June 2018

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Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase

5 June 2018

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5 June 2018

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Beneficial mutations, hitchhiking and the evolution of mutation rates in sexual populations

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase

5 June 2018

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Rates of spontaneous mutation

5 June 2018

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Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

5 June 2018

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Evolution of high mutation rates in experimental populations of E. coli

5 June 2018

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A new reporter cell line to monitor HIV infection and drug susceptibility in vitro

5 June 2018

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Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virus

5 June 2018

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Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

5 June 2018

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High mutation frequencies among Escherichia coli and Salmonella pathogens

5 June 2018

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Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis

5 June 2018

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

5 June 2018

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

5 June 2018

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The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels.

5 June 2018

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

5 June 2018

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Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

5 June 2018

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Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

5 June 2018

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Fitness of an Escherichia coli Mutator Gene

5 June 2018

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Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

5 June 2018

1 reference

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Studies on the biochemical basis of spontaneous mutation. III. Rate model for DNA polymerase-effected nucleotide misincorporation

5 June 2018

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Comparative rates of spontaneous mutation

5 June 2018

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A constant rate of spontaneous mutation in DNA-based microbes

5 June 2018

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Antigenic Diversity Thresholds and the Development of AIDS

5 June 2018

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Heterogeneity of the mutation rates of influenza A viruses: isolation of mutator mutants

5 June 2018

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Engineering attenuated virus vaccines by controlling replication fidelity

5 June 2018

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The cost of replication fidelity in human immunodeficiency virus type 1.

18 August 2018

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A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions

18 August 2018

1 reference

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Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations

18 August 2018

1 reference

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Adaptation in the env gene of HIV-1 and evolutionary theories of disease progression

18 August 2018

1 reference

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Coupling ribose selection to fidelity of DNA synthesis. The role of Tyr-115 of human immunodeficiency virus type 1 reverse transcriptase.

18 August 2018

1 reference

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Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.

18 August 2018

1 reference

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Incidence of mutator strains in Escherichia coli and coliforms in nature.

18 August 2018

1 reference

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Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases

18 August 2018

1 reference

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Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse Gut

18 August 2018

1 reference

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RNA virus evolution via a fitness-space model

2 December 2018

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12 December 2020

Increased polymerase fidelity of lamivudine-resistant HIV-1 variants does not limit their evolutionary potential

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12 December 2020

The origins of eukaryotic gene structure

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12 December 2020

COMPETITION BETWEEN HIGH AND LOW MUTATING STRAINS OF ESCHERICHIA COLI

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12 December 2020

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

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12 December 2020

Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials

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12 December 2020

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1 reference

12 December 2020

10.1016/J.JMB.2012.10.009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23084856%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23084856%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

23084856

1 reference