Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen. (Q41943393)

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21 January 2020

title

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen (English)

1 reference

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21 January 2020

0 references

7

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21 January 2020

Joao Batista da Rocha

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8

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21 January 2020

9

Michael Aschner

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21 January 2020

5

Dejan Milatovic

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21 January 2020

1

Zhaobao Yin

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21 January 2020

4

Haiyan Jiang

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21 January 2020

2

Eunsook Lee

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21 January 2020

author name string

Mingwei Ni

series ordinal

3

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21 January 2020

Lu Rongzhu

series ordinal

6

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21 January 2020

publication date

15 February 2011

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21 January 2020

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21 January 2020

volume

32

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21 January 2020

issue

3

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21 January 2020

page(s)

291-299

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Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity

21 January 2020

cites work

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Manganese disrupts astrocyte glutamine transporter expression and function

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Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain

5 June 2018

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Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells

5 June 2018

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Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes

5 June 2018

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Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina

5 June 2018

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Molecular mechanisms of caspase regulation during apoptosis

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Protective effects on neuronal cells of mouse afforded by ebselen against oxidative stress at multiple steps

5 June 2018

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Astrocyte-mediated methylmercury neurotoxicity

5 June 2018

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Selective impairment of hippocampal neurogenesis by chronic alcoholism: protective effects of an antioxidant.

5 June 2018

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The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update

5 June 2018

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Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen

5 June 2018

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Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain

5 June 2018

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MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells

5 June 2018

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5 June 2018

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Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

5 June 2018

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Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis

5 June 2018

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Caspase-3 activation and DNA fragmentation in primary hippocampal neurons following glutamate excitotoxicity

5 June 2018

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Oxidative stress induces proorphanin FQ and proenkephalin gene expression in astrocytes through p38- and ERK-MAP kinases and NF-kappaB

5 June 2018

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Sustained extracellular signal-regulated kinase activation by 6-hydroxydopamine: implications for Parkinson's disease

5 June 2018

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Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons.

5 June 2018

1 reference

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Ebselen: prospective therapy for cerebral ischaemia

5 June 2018

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Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons

5 June 2018

1 reference

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Astrocytic swelling, phospholipase A2, glutathione and glutamate: interactions in methylmercury-induced neurotoxicity

5 June 2018

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Methylmercury alters glutamate transport in astrocytes

5 June 2018

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Mitochondrial control of cell death

5 June 2018

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5 June 2018

Metals and neuroscience.

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Oxidative stress and gene regulation

5 June 2018

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Redox regulation of signal transduction in mammalian cells

5 June 2018

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Protective effect of ebselen against hydrogen peroxide-induced cytotoxicity and DNA damage in HepG2 cells

5 June 2018

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Low-level methylmercury exposure causes human T-cells to undergo apoptosis: evidence of mitochondrial dysfunction

5 June 2018

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5 June 2018

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Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve

5 June 2018

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Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

5 June 2018

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Role of astrocytes in glutamate homeostasis. Implications for excitotoxicity

5 June 2018

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Kinetic study of the reaction of ebselen with peroxynitrite.

5 June 2018

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Oxidative stress in neurotoxic effects of methylmercury poisoning.

5 June 2018

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The MAPK signaling cascade

5 June 2018

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Methylmercury Poisoning in Iraq

5 June 2018

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The effects of methylmercury on the developing brain

5 June 2018

1 reference

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Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling

5 June 2018

1 reference

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Mechanisms by which mitochondria transport calcium

5 June 2018

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Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity.

5 June 2018

1 reference

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Effect of Methyl Mercury on Phosphorylation, Transport, and Oxidation in Mammalian Mitochondria1

5 June 2018

1 reference

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Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

5 June 2018

1 reference

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Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.

18 August 2018

1 reference

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The use of ebselen for radioprotection in cultured cells and mice.

18 August 2018

1 reference

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Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system

18 August 2018

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Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice

18 August 2018

1 reference

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Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice

18 August 2018

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Selenium compounds counteract the stimulation of ecto-nucleotidase activities in rat cultured cerebellar granule cells: putative correlation with neuroprotective effects

18 August 2018

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Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

18 August 2018

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Manganese induces oxidative impairment in cultured rat astrocytes.

18 August 2018

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Ebselen prevents chronic alcohol-induced rat hippocampal stress and functional impairment.

18 August 2018

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Ebselen attenuates oxidative stress in ischemic astrocytes depleted of glutathione. Comparison with glutathione precursors.

18 August 2018

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Diphenyl ditelluride- and methylmercury-induced hyperphosphorilation of the high molecular weight neurofilament subunit is prevented by organoselenium compounds in cerebral cortex of young rats.

18 August 2018

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Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain.

18 August 2018

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Neuroprotective effects of ebselen on experimental spinal cord injury in rats

18 August 2018

1 reference

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Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+.

18 August 2018

1 reference

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Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures

18 August 2018

1 reference

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Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury

18 August 2018

1 reference

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Mitochondrial extracellular signal-regulated kinases 1/2 (ERK1/2) are modulated during brain development.

18 August 2018

1 reference

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Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

18 August 2018

1 reference

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Temporal and spatial distribution of activated caspase-3 after subdural kainic acid infusions in rat spinal cord

18 August 2018

1 reference

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Apoptotic mitochondrial pathway in neurones and astrocytes after neonatal hypoxia-ischaemia in the rat brain.

18 August 2018

1 reference

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Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase.

18 August 2018

1 reference

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Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Methylmercury has a selective effect on mitochondria in cultured astrocytes in the presence of [U-(13)C]glutamate

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Sensitivity of immature neurons in culture to metal-induced changes in reactive oxygen species and intracellular free calcium.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Combined mechanical trauma and metabolic impairment in vitro induces NMDA receptor-dependent neuronal cell death and caspase-3-dependent apoptosis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Methylmercury-induced depression of neuromuscular transmission in the rat

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079013

Temporal profile and cell subtype distribution of activated caspase-3 following experimental traumatic brain injury

18 August 2018

1 reference

12 December 2020

De novo-synthesized ceramide signals apoptosis in astrocytes via extracellular signal-regulated kinase

1 reference

12 December 2020

Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons

1 reference

12 December 2020

[New treatments in cerebrovascular diseases]

1 reference

12 December 2020

Activation of apoptosis-linked caspase(s) in NMDA-injured brains in neonatal rats

1 reference

12 December 2020

Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures

1 reference

12 December 2020

The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

1 reference

12 December 2020

The role of glutamine as an energy source in the developing rat lung

1 reference

12 December 2020

The mitochondrial permeability transition

1 reference

12 December 2020

A novel biologically active seleno-organic compound—1

1 reference

12 December 2020

A novel biologically active seleno-organic compound--II. Activity of PZ 51 in relation to glutathione peroxidase

1 reference

12 December 2020

Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C?

1 reference

12 December 2020

Mercury level and histochemical distribution in a human brain with Minamata disease following a long-term clinical course of twenty-six years

1 reference

12 December 2020

10.1016/J.NEURO.2011.01.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300091%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300091%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference