Molecular mechanisms of caspase regulation during apoptosis (Q29617861)

Europe PubMed Central

title

Molecular mechanisms of caspase regulation during apoptosis (English)

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30 April 2017

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Riedl SJ

1

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30 April 2017

Shi Y

series ordinal

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15520809

30 April 2017

language of work or name

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30 April 2017

publication date

November 2004

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Nature Reviews Molecular Cell Biology

30 April 2017

published in

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volume

5

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page(s)

897-907

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issue

11

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cites work

The Hallmarks of Cancer

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Mechanisms of caspase activation and inhibition during apoptosis

1 May 2017

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1 May 2017

Caspases: enemies within

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 May 2017

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 May 2017

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1 May 2017

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A structural view of mitochondria-mediated apoptosis

1 May 2017

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 May 2017

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 May 2017

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 May 2017

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Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

1 May 2017

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 May 2017

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 May 2017

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The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 May 2017

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The Bcl2 family: regulators of the cellular life-or-death switch

1 May 2017

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The engagement of Sec61p in the ER dislocation process

1 May 2017

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Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 May 2017

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Structure and mechanism of interleukin-1 beta converting enzyme

1 May 2017

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Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway

1 May 2017

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1 May 2017

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Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

1 May 2017

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The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

1 May 2017

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The atomic-resolution structure of human caspase-8, a key activator of apoptosis

1 May 2017

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The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

1 May 2017

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Dimer formation drives the activation of the cell death protease caspase 9

1 May 2017

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Crystal structure of an invertebrate caspase

1 May 2017

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Structural basis for the activation of human procaspase-7

1 May 2017

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 May 2017

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Conformational restrictions in the active site of unliganded human caspase-3

1 May 2017

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IAP proteins: blocking the road to death's door

1 May 2017

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Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination

1 May 2017

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

1 May 2017

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Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

1 May 2017

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 May 2017

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Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern

1 May 2017

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Livin, a novel inhibitor of apoptosis protein family member

1 May 2017

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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 May 2017

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NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

1 May 2017

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Mechanism of XIAP-mediated inhibition of caspase-9

1 May 2017

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 May 2017

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Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

1 May 2017

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Structure of a serpin-protease complex shows inhibition by deformation

1 May 2017

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 May 2017

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 May 2017

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Structural basis of IAP recognition by Smac/DIABLO

1 May 2017

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Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 May 2017

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 May 2017

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 May 2017

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 May 2017

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

1 May 2017

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

1 May 2017

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 May 2017

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Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

1 May 2017

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Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides

1 May 2017

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Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

1 May 2017

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A unified model for apical caspase activation

1 May 2017

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Insights into the regulatory mechanism for caspase-8 activation

1 May 2017

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 May 2017

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Mechanisms of caspase activation

1 May 2017

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 May 2017

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Worms, life, and death (Nobel lecture).

1 May 2017

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Programmed cell death in animal development

31 March 2020

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Cell death: critical control points

31 March 2020

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An emerging blueprint for apoptosis in Drosophila

31 March 2020

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Apoptosis in the pathogenesis and treatment of disease

31 March 2020

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Apoptosis in the nervous system

31 March 2020

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A matter of life and death

31 March 2020

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Apoptosis genes and autoimmunity.

31 March 2020

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

31 March 2020

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Human ICE/CED-3 protease nomenclature

31 March 2020

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Molecular cloning of the interleukin-1 beta converting enzyme

31 March 2020

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The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease

31 March 2020

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31 March 2020

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Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35.

31 March 2020

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Biochemical pathways of caspase activation during apoptosis

31 March 2020

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Insights into programmed cell death through structural biology

31 March 2020

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Structural biology. Controlling the caspases

31 March 2020

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Apoptosomes: engines for caspase activation

31 March 2020

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Apoptosome: the cellular engine for the activation of caspase-9.

31 March 2020

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Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

31 March 2020

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Caspase-9 and APAF-1 form an active holoenzyme

31 March 2020

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Fas ligand-induced apoptosis

31 March 2020

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The CD95(APO-1/Fas) DISC and beyond

31 March 2020

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Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

31 March 2020

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

31 March 2020

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Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

31 March 2020

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Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

31 March 2020

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HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis

31 March 2020

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Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark

31 March 2020

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Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

31 March 2020

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Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits

31 March 2020

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The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

31 March 2020

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Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim

31 March 2020

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

31 March 2020

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IAP family proteins--suppressors of apoptosis

31 March 2020

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An exegesis of IAPs: salvation and surprises from BIR motifs

31 March 2020

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Understanding IAP function and regulation: a view from Drosophila

31 March 2020

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The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7

31 March 2020

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Structural basis for the inhibition of caspase-3 by XIAP

31 March 2020

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Structural basis of caspase-7 inhibition by XIAP

31 March 2020

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

31 March 2020

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Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

31 March 2020

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Mechanism-based inactivation of caspases by the apoptotic suppressor p35.

31 March 2020

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Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo

31 March 2020

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Characterization of the apoptosis suppressor protein P49 from the Spodoptera littoralis nucleopolyhedrovirus.

31 March 2020

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The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis.

31 March 2020

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A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding

31 March 2020

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Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

31 March 2020

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The Drosophila caspase DRONC is regulated by DIAP1

31 March 2020

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The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis

31 March 2020

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The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC.

31 March 2020

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Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

31 March 2020

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Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

31 March 2020

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Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

31 March 2020

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Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac

31 March 2020

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Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

31 March 2020

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Caspase activation: revisiting the induced proximity model

31 March 2020

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Caspase activation: the induced-proximity model

31 March 2020

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An induced proximity model for caspase-8 activation.

31 March 2020

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Autoproteolytic activation of pro-caspases by oligomerization.

31 March 2020

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Synthetic activation of caspases: artificial death switches

31 March 2020

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Programmed cell death in invertebrates.

31 March 2020

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

31 March 2020

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Identifiers

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

472017

1002939646

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472017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15520809

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30 April 2017

Consolidated OpenCitations Corpus – April 2017