MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. (Q41955439)

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scientific article published on 26 February 2010

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English	MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.	scientific article published on 26 February 2010

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19 January 2020

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs (English)

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Andrew K Sewell

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Rachel E Hewitt

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Scott R Burrows

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Cor Berrevoets

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Reno Debets

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Emma Gostick

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19 January 2020

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Linda Wooldridge

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19 January 2020

Mathew Clement

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Anna Lissina

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Julia Ekeruche

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Bruno Laugel

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19 January 2020

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26 February 2010

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19 January 2020

Journal of Immunology

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19 January 2020

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19 January 2020

3357-3366

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19 January 2020

A new function for LAT and CD8 during CD8-mediated apoptosis that is independent of TCR signal transduction

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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

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Tricks with tetramers: how to get the most from multimeric peptide-MHC.

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Human TCR-binding affinity is governed by MHC class restriction

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CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens

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Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface

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Peptide-MHC class I tetrameric complexes display exquisite ligand specificity.

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190139

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based on heuristic

inferred from PubMed ID database lookup

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

1 reference

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inferred from PubMed ID database lookup

Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0902398

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190139%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190139%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190139%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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