The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. (Q53656560)

16 May 2018

title

The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. (English)

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16 May 2018

author

Andrew K Sewell

9

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16 May 2018

David A Price

object named as

David A Price

8

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author name string

Sarah L Hutchinson

1

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16 May 2018

Linda Wooldridge

2

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Sabrina Tafuro

3

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16 May 2018

Bruno Laugel

4

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16 May 2018

Meir Glick

5

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16 May 2018

Jonathan M Boulter

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Bent K Jakobsen

7

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16 May 2018

language of work or name

English

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publication date

15 April 2003

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16 May 2018

Journal of Biological Chemistry

published in

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volume

278

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16 May 2018

issue

27

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16 May 2018

page(s)

24285-24293

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16 May 2018

Ligand recognition by alpha beta T cell receptors

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The specificity of TCR/pMHC interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Interactions between MHC molecules and co-receptors of the TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The CD8 coreceptor revisited: one chain good, two chains better

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CTL activation is induced by cross-linking of TCR/MHC-peptide-CD8/p56lck adducts in rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Membrane compartmentation is required for efficient T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Membrane compartmentation and the response to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Novel CD8+ T cell antagonists based on beta 2-microglobulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Cytotoxic T-lymphocyte activation involves a cascade of signalling and adhesion events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD3 delta establishes a functional link between the T cell receptor and CD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

A signaling role for the cytoplasmic segment of the CD8 alpha chain detected under limiting stimulatory conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 is needed for development of cytotoxic T cells but not helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Co-engagement of CD8 with the T cell receptor is required for negative selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Antigen-specific release of beta-chemokines by anti-HIV-1 cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Expression, purification, and functional analysis of murine ectodomain fragments of CD8alphaalpha and CD8alphabeta dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

BirA enzyme: production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Complete mapping of a novel HLA A*6801-restricted HIV-1 Tat epitope directly with a rapid modified enzyme-linked immunospot assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

A quantitative assay of peptide-dependent class I assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

CD8 independence and specificity of cytotoxic T lymphocytes restricted by HLA-Aw68. 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Co-capping studies reveal CD8/TCR interactions after capping CD8β polypeptides and intracellular associations of CD8 with p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

The CD8alphabeta co-receptor on double-positive thymocytes binds with differing affinities to the products of distinct class I MHC loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

Mouse MHC class I tetramers that are unable to bind to CD8 reveal the need for CD8 engagement in order to activate naive CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300633200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300633200

1 reference

16 May 2018

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16 May 2018