PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis (Q41957703)

14 October 2017

PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis (English)

1 reference

14 October 2017

Jennifer W Hill

2

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Makoto Fukuda

object named as

Makoto Fukuda

3

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author name string

Yong Xu

1

1 reference

14 October 2017

Laurent Gautron

4

1 reference

14 October 2017

Jong-Woo Sohn

5

1 reference

14 October 2017

Ki-Woo Kim

6

1 reference

14 October 2017

Charlotte E Lee

7

1 reference

14 October 2017

Michelle J Choi

8

1 reference

14 October 2017

Danielle A Lauzon

9

1 reference

14 October 2017

Harveen Dhillon

10

1 reference

14 October 2017

Bradford B Lowell

11

1 reference

14 October 2017

Jeffrey M Zigman

12

1 reference

14 October 2017

Jean J Zhao

13

1 reference

14 October 2017

Joel K Elmquist

14

1 reference

14 October 2017

1 July 2010

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14 October 2017

1 reference

14 October 2017

12

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14 October 2017

88-95

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14 October 2017

1

1 reference

A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Diet-induced obese mice are leptin insufficient after weight reduction.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Molecular and neural mediators of leptin action

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Transcriptional control of brown fat determination by PRDM16

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Obesity and the neuroendocrine control of energy homeostasis: the role of spontaneous locomotor activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The brown adipocyte: update on its metabolic role.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The metabolic syndrome: more than the sum of its parts?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Beta-Adrenergic receptors, diet-induced thermogenesis, and obesity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The phosphoinositide 3-kinase pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Intracellular signalling. Key enzyme in leptin-induced anorexia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Identification of SOCS-3 as a potential mediator of central leptin resistance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Ventromedial hypothalamic knife-cut lesions in rats resistant to dietary obesity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Role of ventromedial hypothalamus on sympathetic efferents of brown adipose tissue.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Hypothalamic Obesity: The Myth of the Ventromedial Nucleus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Hypothalamic obesity, brown adipose tissue, and sympathoadrenal activity in rats.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Sympathetic activity following paraventricular or ventromedial hypothalamic lesions in rats

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Comparison of metabolic alterations in hypothalamic and high fat diet-induced obesity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Monitoring FoxO1 localization in chemically identified neurons

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

PI3K signaling effects in hypothalamic neurons mediated by estrogen

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Fasting increases gene expressions of uncoupling proteins and peroxisome proliferator-activated receptor-γ in brown adipose tissue of ventromedial hypothalamus-lesioned rats

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Disruption of the gene encoding SF-1 alters the distribution of hypothalamic neuronal phenotypes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919367

Biomedicine. A sympathetic defense against obesity

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20620998

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Accelerated norepinephrine turnover in peripheral tissues after ventromedial hypothalamic stimulation in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20620998

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2010.05.002

1 reference

14 October 2017

1 reference

14 October 2017

1 reference