The immunology of the allergy epidemic and the hygiene hypothesis (Q41996494)

15 October 2017

The immunology of the allergy epidemic and the hygiene hypothesis (English)

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15 October 2017

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1

Bart N Lambrecht

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15 October 2017

Hamida Hammad

2

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PubMed ID

28926539

15 October 2017

language of work or name

English

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publication date

1 September 2017

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15 October 2017

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15 October 2017

18

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15 October 2017

1076-1083

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15 October 2017

10

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Asthma: an epidemic of dysregulated immunity

15 October 2017

1 reference

21 January 2018

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The effect of infections on susceptibility to autoimmune and allergic diseases

21 January 2018

1 reference

The allergy epidemics: 1870-2010.

21 January 2018

1 reference

US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up

21 January 2018

1 reference

Hay fever, hygiene, and household size

21 January 2018

1 reference

Siblings, asthma, rhinoconjunctivitis and eczema: a worldwide perspective from the International Study of Asthma and Allergies in Childhood

21 January 2018

1 reference

Early childhood infectious diseases and the development of asthma up to school age: a birth cohort study

21 January 2018

1 reference

Microbes and asthma: Opportunities for intervention

21 January 2018

1 reference

Toward primary prevention of asthma. Reviewing the evidence for early-life respiratory viral infections as modifiable risk factors to prevent childhood asthma

21 January 2018

1 reference

Early Respiratory Infections and the Development of Asthma in the First 27 Years of Life.

21 January 2018

1 reference

Hay fever and asthma in relation to markers of infection in the United States

21 January 2018

1 reference

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

21 January 2018

1 reference

The association between foodborne and orofecal pathogens and allergic sensitisation -- EuroPrevall study.

21 January 2018

1 reference

Prevalence of asthma and atopy in two areas of West and East Germany

21 January 2018

1 reference

Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC).

21 January 2018

1 reference

Hygiene hypothesis and autoimmune diseases

21 January 2018

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Environmental biodiversity, human microbiota, and allergy are interrelated

21 January 2018

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Early infancy microbial and metabolic alterations affect risk of childhood asthma

21 January 2018

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Bacterial microbiota of the upper respiratory tract and childhood asthma

21 January 2018

1 reference

Allergy associations with the adult fecal microbiota: Analysis of the American Gut Project

21 January 2018

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Breastfeeding and asthma and allergies: a systematic review and meta-analysis

21 January 2018

1 reference

Consumption of unprocessed cow's milk protects infants from common respiratory infections

21 January 2018

1 reference

Early-Life Events, Including Mode of Delivery and Type of Feeding, Siblings and Gender, Shape the Developing Gut Microbiota

21 January 2018

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Household siblings and nasal and fecal microbiota in infants.

21 January 2018

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Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios

21 January 2018

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21 January 2018

The immunology of asthma

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New paradigms in type 2 immunity

21 January 2018

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Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites

21 January 2018

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Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

21 January 2018

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Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

21 January 2018

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Antigen-nonspecific recruitment of Th2 cells to the lung as a mechanism for viral infection-induced allergic asthma

21 January 2018

1 reference

Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10

21 January 2018

1 reference

CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel

21 January 2018

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Suppression of allergic airway inflammation by helminth-induced regulatory T cells

21 January 2018

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Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection

21 January 2018

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Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function.

21 January 2018

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Distinguishing benign from pathologic TH2 immunity in atopic children.

21 January 2018

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Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells

21 January 2018

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MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells

21 January 2018

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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

21 January 2018

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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

21 January 2018

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Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood

21 January 2018

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Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells.

21 January 2018

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A switch in regulatory T cells through farm exposure during immune maturation in childhood

21 January 2018

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Saturation of immunoglobulin E (IgE) binding sites by polyclonal IgE does not explain the protective effect of helminth infections against atopy

21 January 2018

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IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses

21 January 2018

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IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking

21 January 2018

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Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity

21 January 2018

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Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity

21 January 2018

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IgE cross-reactivity between house dust mite allergens and Ascaris lumbricoides antigens

21 January 2018

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Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy

21 January 2018

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Neonatal exposure to pneumococcal phosphorylcholine modulates the development of house dust mite allergy during adult life

21 January 2018

1 reference

Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease

21 January 2018

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Natural antibody repertoires: development and functional role in inhibiting allergic airway disease

21 January 2018

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The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

21 January 2018

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Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

21 January 2018

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Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

21 January 2018

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Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen

21 January 2018

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Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussi

21 January 2018

1 reference

Cholera toxin B suppresses allergic inflammation through induction of secretory IgA.

21 January 2018

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Barrier Epithelial Cells and the Control of Type 2 Immunity

21 January 2018

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House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

21 January 2018

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Innate immunological function of TH2 cells in vivo.

21 January 2018

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A tissue checkpoint regulates type 2 immunity.

21 January 2018

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Lung Homeostasis: Influence of Age, Microbes, and the Immune System

21 January 2018

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Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung.

21 January 2018

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First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

21 January 2018

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Lung microbiota promotes tolerance to allergens in neonates via PD-L1.

21 January 2018

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Environmental exposure to endotoxin and its relation to asthma in school-age children

21 January 2018

1 reference

The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21.

21 January 2018

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Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study

21 January 2018

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Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

21 January 2018

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Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

21 January 2018

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Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes

21 January 2018

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Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes

21 January 2018

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Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78

21 January 2018

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Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy.

21 January 2018

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Inhibition of Fc epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

21 January 2018

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The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype

21 January 2018

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A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages

21 January 2018

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A nematode immunomodulator suppresses grass pollen-specific allergic responses by controlling excessive Th2 inflammation.

21 January 2018

1 reference

Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus.

21 January 2018

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Therapeutic potential of larval excretory/secretory proteins of the pig whipworm Trichuris suis in allergic disease.

21 January 2018

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Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.

21 January 2018

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Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

21 January 2018

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Aerobic Exercise Reduces Asthma Phenotype by Modulation of the Leukotriene Pathway

21 January 2018

1 reference

7 January 2021

Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18

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7 January 2021

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

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7 January 2021

The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways

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7 January 2021

Induction and differential regulation of bee venom phospholipase A2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells

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7 January 2021

Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells

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7 January 2021

Group 2 innate lymphoid cell activation in the neonatal lung drives type 2 immunity and allergen sensitization

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7 January 2021

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota.

1 reference

7 January 2021

Macrophage migration inhibitory factor isolated from a parasite inhibited Th2 cytokine production in PBMCs of atopic asthma patients

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7 January 2021

Serum IgE levels in white and metis communities in Saskatchewan

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28926539

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NI.3829

1 reference

15 October 2017

1 reference

PubMed ID

28926539