Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue (Q42120897)

16 October 2017

Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue (English)

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16 October 2017

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Sergio Fernández-Pascual

1

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16 October 2017

André Mukala-Nsengu-Tshibangu

2

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16 October 2017

Rafael Martín Del Río

3

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16 October 2017

Jorge Tamarit-Rodríguez

4

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16 October 2017

language of work or name

English

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publication date

1 May 2004

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16 October 2017

9

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inferred from page(s)

published in

Biochemical Journal

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16 October 2017

379

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16 October 2017

Pt 3

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16 October 2017

721-729

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

16 October 2017

1 reference

Protein measurement with the Folin phenol reagent

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Metabotropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Glucose regulation of glutaminolysis and its role in insulin secretion

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Hyperexpression of GAD in the islets may be relevant but is it sufficient to induce autoimmune insulitis?

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

The GABA network and the pathogenesis of IDDM.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

A role for synaptic vesicles in non-neuronal cells: clues from pancreatic beta cells and from chromaffin cells.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

The stimulus-secretion coupling of glucose-induced insulin release. Environmental influences on L-glutamine oxidation in pancreatic islets

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Stimulus-secretion coupling of amino acid-induced insulin release VII. The B-cell memory for L-glutamine.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a non-metabolizable leucine analogue

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Insulin release: reconciliation of the receptor and metabolic hypotheses. Nutrient receptors in islet cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

The pentose cycle and insulin release in mouse pancreatic islets

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Interrelationship of islet metabolism, adenosine triphosphate content and insulin release

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Glutamate production in islets of Langerhans: properties of phosphate-activated glutaminase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Inhibition of brain glutamate decarboxylase by 2-keto-4-pentenoic acid, a metabolite of allylglycine

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Correlation between GABA release from rat islet beta-cells and their metabolic state

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

An osmotic-sensitive taurine pool is localized in rat pancreatic islet cells containing glucagon and somatostatin

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224127

Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release

17 August 2018

1 reference

12 December 2020

The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets

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12 December 2020

Levels of α-Ketoglutarate and Glutamate in Stimulated Pancreatic β-Cells

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12 December 2020

GABA production in rat islets of Langerhans

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12 December 2020

Nutrient regulation of gamma-aminobutyric acid release from islet beta cells

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12 December 2020

Stimulation of insulin release by L-glutamine

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12 December 2020

Comparison of the effects of leucines, non-metabolizable leucine analogues and other insulin secretagogues on the activity of glutamate dehydrogenase

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12 December 2020

A sensitive fluorometric assay for the determination of DNA

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12 December 2020

The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine

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12 December 2020

Regulation of insulin release by factors that also modify glutamate dehydrogenase

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12 December 2020

Glutamate is not a messenger in insulin secretion

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12 December 2020

Identifiers

DOI

10.1042/BJ20031826

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16 October 2017

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16 October 2017

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