Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+. (Q42162908)

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scientific article published on July 2003

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English	Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+.	scientific article published on July 2003

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5 November 2019

Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+ (English)

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5 November 2019

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Marina Sergeeva

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5 November 2019

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Georg Reiser

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5 November 2019

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Mikhail Strokin

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5 November 2019

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1 July 2003

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5 November 2019

British Journal of Pharmacology

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5 November 2019

139

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5 November 2019

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5 November 2019

1014-1022

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5 November 2019

The biochemistry of n-3 polyunsaturated fatty acids

1 reference

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Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue

1 reference

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Inhibition of neuronal apoptosis by polyunsaturated fatty acids

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26 October 2017

Polyunsaturated fatty acid synthesis and release by brain-derived cells in vitro.

1 reference

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26 October 2017

Plasmalogens: biosynthesis and functions

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Calcium-independent phospholipase A(2): structure and function.

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Polyunsaturated fatty acids are potent neuroprotectors

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Dietary polyunsaturated fatty acids and inflammatory mediator production

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Regional distribution, ontogeny, purification, and characterization of the Ca2+-independent phospholipase A2 from rat brain

1 reference

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Molecular characterization of cytosolic phospholipase A2-beta

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The human calcium-independent phospholipase A2 gene multiple enzymes with distinct properties from a single gene

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Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism

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26 October 2017

Inhibition of phospholipase A2-mediated arachidonic acid release by cyclic AMP defines a negative feedback loop for P2Y receptor activation in Madin-Darby canine kidney D1 cells

1 reference

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26 October 2017

Critical duration of intracellular Ca2+ response required for continuous translocation and activation of cytosolic phospholipase A2.

1 reference

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Oxidative stress hypothesis in Alzheimer's disease

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26 October 2017

p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2

1 reference

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26 October 2017

Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate

1 reference

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26 October 2017

Antagonistic effects of dietary arachidonic acid and n-3 polyunsaturated fatty acids

1 reference

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26 October 2017

Fatty acids enter cells by simple diffusion

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26 October 2017

How do long-chain free fatty acids cross cell membranes?

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26 October 2017

Arachidonic acid as a neurotoxic and neurotrophic substance

1 reference

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26 October 2017

cPLA2 is phosphorylated and activated by MAP kinase

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Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.

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26 October 2017

U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells

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Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones.

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

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Coexpression of phospholipase A2 isoforms in rat striatal astrocytes

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Interleukin-1 enhances the ATP-evoked release of arachidonic acid from mouse astrocytes

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Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes

1 reference

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17 August 2018

Arachidonic acid and docosahexaenoic acid suppress thrombin-evoked Ca2+ response in rat astrocytes by endogenous arachidonic acid liberation.

1 reference

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1 reference

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17 August 2018

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1 reference

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1 reference

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1 reference

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1 reference

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17 August 2018

Protein kinase C inhibitors stimulate arachidonic and docosahexaenoic acids release from uterine stromal cells through a Ca2+-independent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous activation of p38 MAPK and p42/44 MAPK by ATP stimulates the K+ current ITREK in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of different phospholipase A2 isoforms by TNF-alpha and IL-1beta in adult rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced production of PGE2 and PGF2 alpha from decidual cell cultures supplemented with N-3 polyunsaturated fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of lipoxygenase pathway in docosapentaenoic acid-induced inhibition of platelet aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-adrenergic receptor mediates arachidonic acid release in spinal cord neurons independent of inositol phospholipid turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans n-3 eicosapentaenoic and docosahexaenoic acid isomers exhibit different inhibitory effects on arachidonic acid metabolism in human platelets compared to the respective cis fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-evoked arachidonic acid mobilization in astrocytes is via a P2Y-purinergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docosahexaenoic acid and signaling pathways in rabbit colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic guanosine monophosphate-dependent protein kinase is targeted to intermediate filaments and phosphorylates vimentin in A23187-stimulated human neutrophils

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic effects of acetylcholine and glutamate on the release of arachidonic acid from cultured striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of thrombin-induced calcium signals in rat astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-induced arachidonic acid release in cultured astrocytes is mediated by Gi protein coupled P2Y1 and P2Y2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12839876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for PKC epsilon and MAP kinase in bradykinin-induced arachidonic acid release in rabbit CCD cells

1 reference

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12 December 2020

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10.1038/SJ.BJP.0705326

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12839876%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12839876%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12839876%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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