Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells. (Q42231996)

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10 March 2020

title

Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells (English)

1 reference

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10 March 2020

1 reference

12

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10 March 2020

Jean-Pierre de Villartay

11

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10 March 2020

author name string

J Rivière

1

1 reference

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10 March 2020

J Hauer

2

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10 March 2020

L Poirot

3

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10 March 2020

J Brochet

4

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10 March 2020

P Souque

5

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10 March 2020

K Mollier

6

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10 March 2020

A Gouble

7

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10 March 2020

P Charneau

8

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10 March 2020

A Fischer

9

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10 March 2020

F Pâques

10

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10 March 2020

publication date

13 March 2014

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10 March 2020

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10 March 2020

volume

21

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issue

5

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10 March 2020

page(s)

529-532

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20 years of gene therapy for SCID.

10 March 2020

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Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks

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Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

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Proteasome activity restricts lentiviral gene transfer into hematopoietic stem cells and is down-regulated by cytokines that enhance transduction.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Reduced immunoglobulin class switch recombination in the absence of Artemis

1 reference

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