The use of a TLR2 agonist-based adjuvant for enhancing effector and memory CD8 T-cell responses (Q42244917)

19 October 2017

The use of a TLR2 agonist-based adjuvant for enhancing effector and memory CD8 T-cell responses (English)

1 reference

19 October 2017

0 references

Matthew R Olson

2

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Brendon Chua

Brendon Y Chua

1

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Sammy Bedoui

Sammy Bedoui

3

0 references

Stephen J. Turner

Stephen J Turner

6

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David Jackson

David C Jackson

7

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author name string

Toshiki Sekiya

4

1 reference

PubMed ID

24394993

19 October 2017

Chinn Y Wong

5

1 reference

19 October 2017

7 January 2014

1 reference

Immunology & Cell Biology

19 October 2017

1 reference

19 October 2017

92

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19 October 2017

4

1 reference

19 October 2017

377-383

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Mycobacterium tuberculosis Rv0577, a novel TLR2 agonist, induces maturation of dendritic cells and drives Th1 immune response.

19 October 2017

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

TLR2 engagement on dendritic cells promotes high frequency effector and memory CD4 T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Soluble proteins induce strong CD8+ T cell and antibody responses through electrostatic association with simple cationic or anionic lipopeptides that target TLR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

The context of epitope presentation can influence functional quality of recalled influenza A virus-specific memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Intranasal lipopeptide primes lung-resident memory CD8+ T cells for long-term pulmonary protection against influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

The synthetic TLR2 agonist BPPcysMPEG leads to efficient cross-priming against co-administered and linked antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Intranasal immunization with recombinant PspA fused with a flagellin enhances cross-protective immunity against Streptococcus pneumoniae infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

CpG-DNA aided cross-presentation of soluble antigens by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Hepatitis C VLPs delivered to dendritic cells by a TLR2 targeting lipopeptide results in enhanced antibody and cell-mediated responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Alum adjuvant: some of the tricks of the oldest adjuvant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Adjuvants and antibody production: dispelling the myths associated with Freund's complete and other adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

CpG DNA induces cyclooxygenase-2 expression and prostaglandin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

TLR2-dependent induction of IL-10 and Foxp3+ CD25+ CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Constitutive class I-restricted exogenous presentation of self antigens in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen-induced T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

inferred from DOI database lookup

7 January 2021

based on heuristic

Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

inferred from DOI database lookup

7 January 2021

based on heuristic

Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.102

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ICB.2013.102

1 reference

19 October 2017

1 reference

PubMed ID

24394993