Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling (Q42265452)

19 October 2017

Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling (English)

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19 October 2017

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Carlos Gorbea

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19 October 2017

Martin Rechsteiner

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2

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19 October 2017

Jesús G Vallejo

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19 October 2017

Neil E Bowles

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19 October 2017

language of work or name

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1 October 2013

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19 October 2017

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19 October 2017

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19 October 2017

ra86

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19 October 2017

295

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Innate immune recognition

19 October 2017

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Sensing of viral infection and activation of innate immunity by toll-like receptor 3

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Antiviral responses induced by the TLR3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

The TLR3 signaling complex forms by cooperative receptor dimerization

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

DUBA: a deubiquitinase that regulates type I interferon production

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

A ubiquitin-like system mediates protein lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Cleaved/associated TLR3 represents the primary form of the signaling receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Characterization of a nonclathrin endocytic pathway: membrane cargo and lipid requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

ARF proteins: roles in membrane traffic and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Large-scale mapping of human protein-protein interactions by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Membrane recruitment of effector proteins by Arf and Rab GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Identification and characterization of a family of Rab11-interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Rab11 regulates recycling through the pericentriolar recycling endosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Rab 7: an important regulator of late endocytic membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Ubiquitylation and autophagy in the control of bacterial infections and related inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Autophagy in regulation of Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

Grp1-associated scaffold protein (GRASP) is a regulator of the ADP ribosylation factor 6 (Arf6)-dependent membrane trafficking pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

A role for Toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

TLR3 deficiency in patients with herpes simplex encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004301

10.1126/SCISIGNAL.2004301

21 January 2018

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DOI

1 reference

19 October 2017

1 reference