EGFR signaling pathway and related-miRNAs in age-related diseases: the example of miR-221 and miR-222. (Q42396355)

29 October 2017

1 reference

title

EGFR signaling pathway and related-miRNAs in age-related diseases: the example of miR-221 and miR-222. (English)

1 reference

29 October 2017

3

1 reference

29 October 2017

Ana L Teixeira

1

1 reference

PMC publication ID

3516830

29 October 2017

Mónica Gomes

series ordinal

2

1 reference

29 October 2017

7 December 2012

1 reference

29 October 2017

Frontiers in Genetics

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29 October 2017

3

1 reference

29 October 2017

286

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MicroRNAs as newer therapeutic targets: A big hope from a tiny player

29 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNAs in cancers and neurodegenerative disorders

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma

28 May 2018

1 reference

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MicroRNA expression profiling of NGF-treated PC12 cells revealed a critical role for miR-221 in neuronal differentiation

28 May 2018

1 reference

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MicroRNAs in neural cell development and brain diseases

28 May 2018

1 reference

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Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer

28 May 2018

1 reference

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MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer

28 May 2018

1 reference

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BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina.

28 May 2018

1 reference

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TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer

28 May 2018

1 reference

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Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation.

28 May 2018

1 reference

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MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways

28 May 2018

1 reference

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Role of matrix metalloproteinase-3 in neurodegeneration

28 May 2018

1 reference

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EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

28 May 2018

1 reference

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Genetic determinants at the interface of cancer and neurodegenerative disease

28 May 2018

1 reference

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Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate.

28 May 2018

1 reference

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The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

28 May 2018

1 reference

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Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer

28 May 2018

1 reference

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Castration-resistant prostate cancer: locking up the molecular escape routes

28 May 2018

1 reference

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MicroRNAs and cancer--new paradigms in molecular oncology

28 May 2018

1 reference

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The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

EGFR-targeted therapies in lung cancer: predictors of response and toxicity

28 May 2018

1 reference

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Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

28 May 2018

1 reference

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Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy

28 May 2018

1 reference

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The epidermal growth factor receptor: from development to tumorigenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

A MicroRNA feedback circuit in midbrain dopamine neurons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Impaired microRNA processing enhances cellular transformation and tumorigenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Epidermal growth factor receptor mutations in lung cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNA signatures in human cancers

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNA gene expression deregulation in human breast cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Prostate epithelial cell differentiation and its relevance to the understanding of prostate cancer therapies

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Impact of EGFR genetic variants on glioma risk and patient outcome.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

16 August 2018

1 reference

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Detection of EGF-dependent microRNAs of the fetal mouse submandibular gland at embryonic day 13.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Molecular alterations of EGFR and PTEN in prostate cancer: association with high-grade and advanced-stage carcinomas.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Combined analysis of EGF+61G>A and TGFB1+869T>C functional polymorphisms in the time to androgen independence and prostate cancer susceptibility

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

MicroRNAs and prostate cancer

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516830

White matter damage is associated with matrix metalloproteinases in vascular dementia

3 November 2018

1 reference

12 December 2020

Epidermal growth factor receptor R497K polymorphism is a favorable prognostic factor for patients with colorectal carcinoma

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12 December 2020

Influence of TGFB1+869T>C functional polymorphism in non-small cell lung cancer (NSCLC) risk

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12 December 2020

PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner

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12 December 2020

Genetic Polymorphism in EGF Is Associated with Prostate Cancer Aggressiveness and Progression-Free Interval in Androgen Blockade-Treated Patients

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12 December 2020

Identifiers

DOI

10.3389/FGENE.2012.00286

1 reference

29 October 2017

1 reference

PMC publication ID

3516830

29 October 2017

PubMed publication ID

23233863

1 reference

PMC publication ID

3516830