p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair (Q42443549)

31 October 2017

title

p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair (English)

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31 October 2017

Gisa S Boehden

1

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31 October 2017

Nuray Akyüz

series ordinal

2

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31 October 2017

Klaus Roemer

series ordinal

3

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31 October 2017

Lisa Wiesmüller

series ordinal

4

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31 October 2017

language of work or name

English

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publication date

1 June 2003

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31 October 2017

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31 October 2017

volume

22

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31 October 2017

issue

26

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31 October 2017

page(s)

4111-4117

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The N terminus of p53 regulates its dissociation from DNA.

31 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Yeast base excision repair: interconnections and networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Evidence for a role for DNA polymerase beta in mammalian meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Modulation of cell proliferation and gene expression by a p53-estrogen receptor hybrid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Functional interaction of p53 and BLM DNA helicase in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

Identification of a p53 response element in the promoter region of the hMSH2 gene required for expression in A2780 ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

DNA substrate dependence of p53-mediated regulation of double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Reduced ligation during DNA base excision repair supported by BRCA2 mutant cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Solution conformation of an essential region of the p53 transactivation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Dissociation of the recombination control and the sequence-specific transactivation function of P53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Links between replication, recombination and genome instability in eukaryotes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53 and recombination intermediates: role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Potential roles for p53 in nucleotide excision repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Nuclear and mitochondrial apoptotic pathways of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A role for p53 in the frequency and mechanism of mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Cloning, purification and characterization of DNA polymerase beta from Xenopus laevis--studies on its potential role in DNA-end joining

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A function in apoptosis other than transactivation inherent in the NH2-terminal domain of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Homologous recombinational repair of DNA ensures mammalian chromosome stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

A role for p53 in base excision repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Association of p53 and MSH2 with recombinative repair complexes during S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206632

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206632

1 reference

Dimensions Publication ID

31 October 2017

1031893716

0 references

1 reference