ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney (Q42466844)

1 November 2017

ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney (English)

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1 November 2017

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David J Nikolic-Paterson

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David J Nikolic-Paterson

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3

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author name string

Frank Y Ma

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1

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PubMed ID

25298527

1 November 2017

Greg H Tesch

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2

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PubMed ID

25298527

1 November 2017

language of work or name

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8 October 2014

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American Journal of Physiology - Renal Physiology

1 November 2017

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1 November 2017

307

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1 November 2017

F1263-73

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1 November 2017

11

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Mitogen-activated protein kinases in innate immunity

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TAK1, more than just innate immunity

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c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation

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In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice

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"Go upstream, young man": lessons learned from the p38 saga

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Differential roles of ASK1 and TAK1 in Helicobacter pylori-induced cellular responses

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Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis

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Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling.

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IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis.

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JNK signalling in human and experimental renal ischaemia/reperfusion injury.

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Blockade of CCR2 ameliorates progressive fibrosis in kidney.

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Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells.

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C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice.

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A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis.

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Mitogen activated protein kinases in renal fibrosis

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TGF-β1-activated kinase-1 regulates inflammation and fibrosis in the obstructed kidney.

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

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Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction

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Critical role of apoptosis signal-regulating kinase 1 in aldosterone/salt-induced cardiac inflammation and fibrosis.

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Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.

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Depletion of apoptosis signal-regulating kinase 1 prevents bile duct ligation-induced necroinflammation and subsequent peribiliary fibrosis.

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Angiotensin II-induced reactive oxygen species and the kidney

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Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling

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Rotenone remarkably attenuates oxidative stress, inflammation, and fibrosis in chronic obstructive uropathy

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Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats.

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Apoptosis signal-regulating kinase 1 is crucial for oxidative stress-induced but not for osmotic stress-induced hepatocyte cell death

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Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury

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Important role of apoptosis signal-regulating kinase 1 in ischemic acute kidney injury

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Molecular cloning and characterization of the mouse apoptosis signal-regulating kinase 1.

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ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

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Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.

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Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats

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Regulation of potassium (K) handling in the renal collecting duct

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Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model

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21 January 2018

Identifiers

DOI

1 reference

1 November 2017

1 reference

PubMed ID

25298527