p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain. (Q42483752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Xin-Fu Zhou

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Yan-Jiang Wang

1

1 reference

ORCID Public Data File 2021

Chang-Yue Gao

5

object named as

Chang-Yue Gao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

6

Xiao-Hong Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Xin Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Jian-Jun Lu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Qiao-Xin Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Yin Sun

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Miao Yang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Genevieve Evin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Jin-Hua Zhong

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Colin Masters

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

2292-2304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6633040/fullTextXML

inferred from PubMed Central ID database lookup

cites work

P75 neurotrophin receptor in the nucleus basalis of meynert in relation to age, sex, and Alzheimer's disease

1 reference

12 December 2020

Enlarged cholinergic forebrain neurons and improved spatial learning in p75 knockout mice

1 reference

12 December 2020

Brain trauma in aged transgenic mice induces regression of established abeta deposits

1 reference

12 December 2020

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

1 reference

12 December 2020

Neurotrophins induce death of hippocampal neurons via the p75 receptor

1 reference

12 December 2020

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

1 reference

12 December 2020

Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system

1 reference

12 December 2020

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

1 reference

12 December 2020

Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.

1 reference

12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

1 reference

12 December 2020

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

1 reference

12 December 2020

Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients

1 reference

12 December 2020

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

1 reference

12 December 2020

Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice

1 reference

12 December 2020

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

1 reference

12 December 2020

p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity.

1 reference

12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1 reference

12 December 2020

Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).

1 reference

12 December 2020

APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

1 reference

12 December 2020

Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD

1 reference

12 December 2020

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains

1 reference

12 December 2020

Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.

1 reference

12 December 2020

A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

1 reference

12 December 2020

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

1 reference

12 December 2020

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

1 reference

12 December 2020

Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

1 reference

12 December 2020

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

1 reference

12 December 2020

Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

1 reference

12 December 2020

Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis

1 reference

12 December 2020

TACE-induced cleavage of NgR and p75NTRin dorsal root ganglion cultures disinhibits outgrowth and promotes branching of neurites in the presence of inhibitory CNS myelin

1 reference

12 December 2020

Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?

1 reference

12 December 2020

Congo red and protein aggregation in neurodegenerative diseases

1 reference

12 December 2020

Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives

1 reference

12 December 2020

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

12 December 2020

Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro.

1 reference

12 December 2020

Intramuscular delivery of a single chain antibody gene reduces brain Abeta burden in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice.

1 reference

12 December 2020

Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?

1 reference

12 December 2020

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

1 reference

12 December 2020

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

1 reference

12 December 2020

Amyloid precursor protein trafficking, processing, and function

1 reference

12 December 2020

Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures

1 reference

12 December 2020

Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction

1 reference

12 December 2020

Enhanced spatial memory and hippocampal long-term potentiation in p75 neurotrophin receptor knockout mice.

1 reference

12 December 2020

Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

1 reference

12 December 2020

p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model

1 reference

12 December 2020

The role of the p75 neurotrophin receptor in cholinergic dysfunction in Alzheimer's disease

1 reference

12 December 2020

Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism

1 reference

12 December 2020

The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo

1 reference

12 December 2020

Amyloid-beta peptides stimulate the expression of the p75(NTR) neurotrophin receptor in SHSY5Y human neuroblastoma cells and AD transgenic mice

1 reference

12 December 2020

Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat.

1 reference

12 December 2020

Intramuscular delivery of a single chain antibody gene prevents brain Aβ deposition and cognitive impairment in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

12 December 2020

Modified immunotherapies against Alzheimer's disease: toward safer and effective amyloid clearance

1 reference

12 December 2020

Mesenchymal and neuronal cell expression of the p75 neurotrophin receptor gene occur by different mechanisms

1 reference

12 December 2020

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

12 December 2020

Variable-interval probe test as a tool for repeated measurements of spatial memory in the water maze.

1 reference

12 December 2020

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

12 December 2020

Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration.

1 reference

12 December 2020

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

12 December 2020

Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

1 reference

12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells

1 reference

12 December 2020

Targeted intraparenchymal delivery of human NGF by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition

1 reference

12 December 2020

10.1523/JNEUROSCI.2733-10.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

release_2ne2bj6xa5cvdaynhiz4nujguq

22 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2ne2bj6xa5cvdaynhiz4nujguq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307265%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21307265

1 reference