Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha (Q42484804)

1 November 2017

Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha (English)

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1 November 2017

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Brent R DeGeorge

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1 November 2017

Yoshihiro Higuchi

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1 November 2017

Maria A Brown

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1 November 2017

Jin Zhang

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1 November 2017

Hajime Funakoshi

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1 November 2017

Gregory Gibson

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1 November 2017

Charles F McTiernan

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1 November 2017

Toru Kubota

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1 November 2017

W Keith Jones

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1 November 2017

Arthur M Feldman

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1 November 2017

language of work or name

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30 September 2005

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American Journal of Physiology Heart and Circulatory Physiology

1 November 2017

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1 November 2017

290

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H590-8

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Akt signaling pathway in pacing-induced heart failure

1 November 2017

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Series introduction: the transcription factor NF-kappaB and human disease

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Cardiac-specific blockade of NF-kappaB in cardiac pathophysiology: differences between acute and chronic stimuli in vivo

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Cardiac-specific abrogation of NF- kappa B activation in mice by transdominant expression of a mutant I kappa B alpha

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

The role of tumor necrosis factor in the pathophysiology of heart failure

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-alpha-induced cardiomyopathy.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

NF-kappaB in cardiovascular disease: diverse and specific effects of a "general" transcription factor?

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Anti-tumor necrosis factor-alpha antibody limits heart failure in a transgenic model

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Blockade of NF-kappaB improves cardiac function and survival without affecting inflammation in TNF-alpha-induced cardiomyopathy.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Pacing-induced heart failure: a model to study the mechanism of disease progression and novel therapy in heart failure.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

In vivo TNF-alpha inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

A decade of discoveries in cardiac biology

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Akt/protein kinase B promotes organ growth in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Ras, Akt, and mechanotransduction in the cardiac myocyte

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Insulin resistance and inflammatory activation in older patients with systolic and diastolic heart failure

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

TNF-α signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-α receptor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00379.2005

10.1152/AJPHEART.00379.2005

21 January 2018

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DOI

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1 November 2017

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