Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death (Q42504611)

1 November 2017

Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death (English)

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1 November 2017

endoplasmic reticulum

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Nozaki S

1

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1 November 2017

Sledge Jr GW

series ordinal

2

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1 November 2017

Nakshatri H

series ordinal

3

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1 November 2017

language of work or name

English

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publication date

1 April 2001

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1 November 2017

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1 November 2017

20

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1 November 2017

17

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1 November 2017

2178-2185

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204292

1 November 2017

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV

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Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153

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Interactions between an HMG-1 protein and members of the Rel family

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7 January 2021

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

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7 January 2021

Clonal dominance detected in metastases but not primary tumors of retrovirally marked human breast carcinoma injected into nude mice

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Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.

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7 January 2021

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents

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7 January 2021

Paclitaxel activation of the GADD153 promoter through a cellular injury response element containing an essential Sp1 binding site

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7 January 2021

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia

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Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta

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7 January 2021

Functional interference of Sp1 and NF-kappaB through the same DNA binding site

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7 January 2021

Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic

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DNA damage-inducible genes as biomarkers for exposures to environmental agents

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7 January 2021

Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB.

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7 January 2021

The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

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7 January 2021

An HMG-like protein that can switch a transcriptional activator to a repressor.

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7 January 2021

Systemic gene therapy with p53 reduces growth and metastases of a malignant human breast cancer in nude mice

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7 January 2021

Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells

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7 January 2021

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

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7 January 2021

NF-kappaB as a primary regulator of the stress response

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7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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7 January 2021

Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells

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7 January 2021

Induction of growth arrest and DNA damage-inducible genes Gadd45 and Gadd153 in primary rodent embryonic cells following exposure to methylmercury.

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7 January 2021

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

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7 January 2021

Isolation, characterization and chromosomal localization of the human GADD153 gene

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7 January 2021

Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide

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7 January 2021

The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland

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7 January 2021

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

CHOP/GADD153 gene expression response to cellular stresses inhibited by prior exposure to ultraviolet light wavelength band C (UVC). Inhibitory sequence mediating the UVC response localized to exon 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

C/EBPbeta, but not C/EBPalpha, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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7 January 2021

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Morpholino antisense oligomers: the case for an RNase H-independent structural type

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Identification of novel stress-induced genes downstream of chop

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204292

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204292

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Dimensions Publication ID

1 November 2017

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