The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis (Q42518511)

1 November 2017

The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis (English)

1 reference

1 November 2017

Ana Bravo

3

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Angel Ramirez

object named as

Angel Ramirez

4

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Jesus M. Paramio

object named as

Jesus M Paramio

2

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author name string

Mirentxu Santos

1

1 reference

PubMed ID

11889133

1 November 2017

José L Jorcano

5

1 reference

PubMed ID

11889133

1 November 2017

language of work or name

English

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publication date

11 March 2002

1 reference

Journal of Biological Chemistry

1 November 2017

9

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based on heuristic

inferred from page(s)

published in

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1 November 2017

277

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1 November 2017

21

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1 November 2017

19122-19130

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Intermediate filaments: structure, dynamics, function, and disease

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Intermediate filaments in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Modulation of cell proliferation by cytokeratins K10 and K16

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Ectopic synthesis of epidermal cytokeratins in pancreatic islet cells of transgenic mice interferes with cytoskeletal order and insulin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The role of keratin subfamilies and keratin pairs in the formation of human epidermal intermediate filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Assembly dynamics of epidermal keratins K1 and K10 in transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The genetic basis of epidermolytic hyperkeratosis: a disorder of differentiation-specific epidermal keratin genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Delays in malignant tumor development in transgenic mice by forced epidermal keratin 10 expression in mouse skin carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Functional roles of Akt signaling in mouse skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Exocrine pancreatic disorders in transsgenic mice expressing human keratin 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Forced expression of keratin 16 alters the adhesion, differentiation, and migration of mouse skin keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Akt participation in the Wnt signaling pathway through Dishevelled

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The INK4 family of cell cycle inhibitors in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Changes in keratin gene expression during terminal differentiation of the keratinocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201001200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201001200

1 reference

1 November 2017

1 reference

PubMed ID

11889133