Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity. (Q42637221)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19614978%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity (English)

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2 February 2020

1 reference

9

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2 February 2020

Paul Simons

6

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2 February 2020

author name string

Atsuko Kimura

1

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2 February 2020

Paula L Stevenson

2

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2 February 2020

Roderick N Carter

3

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2 February 2020

Gavin Maccoll

4

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2 February 2020

Karen L French

5

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2 February 2020

Raya Al-Shawi

7

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2 February 2020

Valerie Kelly

8

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2 February 2020

Megan C Holmes

10

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2 February 2020

language of work or name

English

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publication date

15 July 2009

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European Journal of Neuroscience

2 February 2020

published in

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2 February 2020

volume

30

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2 February 2020

issue

2

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2 February 2020

page(s)

299-306

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Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass

2 February 2020

cites work

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S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

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Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors

27 May 2018

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Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation

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Serotonin 5-HT(2C) receptors regulate anxiety-like behavior

27 May 2018

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Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze.

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Selective activation of 5-HT(2C) receptors stimulates GABA-ergic function in the rat substantia nigra pars reticulata: a combined in vivo electrophysiological and neurochemical study

27 May 2018

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5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation

27 May 2018

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Differential effects of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-hydroxytryptamine(2C) receptor-mediated responses

27 May 2018

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Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

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The role of 5-HT2C receptors in affective disorders

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Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade

27 May 2018

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Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.

27 May 2018

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Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration

27 May 2018

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Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.

27 May 2018

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Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission

27 May 2018

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Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims

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Influence of the 5-HT(2C) receptor antagonist SB242,084 on behaviour produced by the 5-HT(2) agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine

27 May 2018

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SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system

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A review of central 5-HT receptors and their function

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Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study

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27 May 2018

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27 May 2018

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27 May 2018

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16 August 2018

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Activation of the brain 5-HT2C receptors causes hypolocomotion without anxiogenic-like cardiovascular adjustments in mice

16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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Anxiogenic effects in the rat elevated plus-maze of 5-HT(2C) agonists into ventral but not dorsal hippocampus.

16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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16 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19614978

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19614978

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1460-9568.2009.06831.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19614978%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19614978%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

19614978

1 reference