Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network. (Q42702094)

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4 March 2020

title

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network (English)

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8

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Clémence D Côté

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author name string

Brittany A Rasmussen

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Frank A Duca

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Melika Zadeh-Tahmasebi

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Joseph A Baur

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Mira Daljeet

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Danna M Breen

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Tony K T Lam

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language of work or name

English

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publication date

6 April 2015

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4 March 2020

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volume

21

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page(s)

498-505

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issue

5

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https://scigraph.springernature.com/pub.10.1038/nm.3821

4 March 2020

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cites work

Resveratrol improves health and survival of mice on a high-calorie diet

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Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats

21 January 2018

1 reference

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

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Central administration of resveratrol improves diet-induced diabetes.

21 January 2018

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Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

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SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

21 January 2018

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Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

21 January 2018

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Pharmacokinetics, tissue distribution and excretion study of resveratrol and its prodrug 3,5,4'-tri-O-acetylresveratrol in rats

21 January 2018

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Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.

21 January 2018

1 reference

SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

21 January 2018

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Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.

21 January 2018

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Pilot study of resveratrol in older adults with impaired glucose tolerance.

21 January 2018

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SirT1 gain of function increases energy efficiency and prevents diabetes in mice

21 January 2018

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

21 January 2018

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Sirt1 protects against high-fat diet-induced metabolic damage

21 January 2018

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SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

21 January 2018

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

21 January 2018

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Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence

21 January 2018

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The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

21 January 2018

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Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes.

21 January 2018

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Hormonal signaling in the gut.

21 January 2018

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Jejunal leptin-PI3K signaling lowers glucose production.

21 January 2018

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Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production

21 January 2018

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Cooperation between brain and islet in glucose homeostasis and diabetes

21 January 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

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Overfeeding rapidly induces leptin and insulin resistance

21 January 2018

1 reference

Therapeutic potential of resveratrol: the in vivo evidence

21 January 2018

1 reference

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

21 January 2018

1 reference

Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA).

21 January 2018

1 reference

Hypothalamic K(ATP) channels control hepatic glucose production

21 January 2018

1 reference

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

21 January 2018

1 reference

High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

21 January 2018

1 reference

Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance

21 January 2018

1 reference

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

21 January 2018

1 reference

Duodenal mucosal protein kinase C-δ regulates glucose production in rats

21 January 2018

1 reference

Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production.

21 January 2018

1 reference

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

21 January 2018

1 reference

Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus

21 January 2018

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12 December 2020

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12 December 2020

Duodenal activation of cAMP-dependent protein kinase induces vagal afferent firing and lowers glucose production in rats

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12 December 2020

Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats

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12 December 2020

Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats.

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12 December 2020

Identifiers

DOI

10.1038/NM.3821

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849131%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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