Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect (Q42730712)

5 November 2017

Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect (English)

1 reference

5 November 2017

0 references

1 reference

6

Satoshi Takeuchi

1 reference

5 November 2017

Gaku Tsuji

1

1 reference

5 November 2017

Masakazu Takahara

2

1 reference

5 November 2017

Hiroshi Uchi

3

1 reference

5 November 2017

Tetsuo Matsuda

4

1 reference

5 November 2017

Takahito Chiba

5

1 reference

5 November 2017

Fumiko Yasukawa

7

1 reference

5 November 2017

Yoichi Moroi

8

1 reference

5 November 2017

Masutaka Furue

9

1 reference

5 November 2017

language of work or name

English

0 references

publication date

14 July 2011

1 reference

Journal of Investigative Dermatology

5 November 2017

1 reference

5 November 2017

132

1 reference

5 November 2017

59-68

1 reference

5 November 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/jid.2011.194

5 November 2017

0 references

cites work

Suppression of ultraviolet B exposure-mediated activation of NF-kappaB in normal human keratinocytes by resveratrol

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure of normal human dermal fibroblasts results in AhR-dependent and -independent changes in gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Ketoconazole in atopic dermatitis: therapeutic response is correlated with decrease in serum IgE

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Interleukin-8, a chemotactic and inflammatory cytokine

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Oxidative stress in the pathogenesis of skin disease

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

The 500 Dalton rule for the skin penetration of chemical compounds and drugs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Effects of an acidic beverage (Coca-Cola) on absorption of ketoconazole

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

The role of Malassezia in atopic dermatitis affecting the head and neck of adults

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Response of scalp psoriasis to oral ketoconazole

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Role of antifungal agents in the treatment of seborrheic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Molecular determinants of species-specific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Relationship between clinical features and blood levels of pentachlorodibenzofuran in patients with Yusho.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Nrf2 signaling in coordinated activation of antioxidant gene expression

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Coordinate regulation of Phase I and II xenobiotic metabolisms by the Ah receptor and Nrf2.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Induction of cytochrome P450 1A1 by ketoconazole and itraconazole but not fluconazole in murine and human hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Resveratrol protects human keratinocytes HaCaT cells from UVA-induced oxidative stress damage by downregulating Keap1 expression

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Origins of individual variability in P4501A induction

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Identification of a novel mechanism of regulation of Ah (dioxin) receptor function

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Inhibitory or scavenging action of ketoconazole and ciclopiroxolamine against reactive oxygen species released by primed inflammatory cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

The Combination of Benzo[a]pyrene and Ultraviolet A Causes an In Vivo Time-related Accumulation of DNA Damage in Mouse Skin¶

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

RelB, a new partner of aryl hydrocarbon receptor-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Increased risk of diabetes and polychlorinated biphenyls and dioxins: a 24-year follow-up study of the Yucheng cohort

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Introducing the "TCDD-inducible AhR-Nrf2 gene battery"

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.194

7 January 2021

Identifiers

DOI

10.1038/JID.2011.194

1 reference

5 November 2017

1 reference