GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins (Q42734763)

6 November 2017

GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins (English)

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6 November 2017

10

Alfred Wittinghofer

1 reference

6 November 2017

Peter J Cullen

11

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Oliver Daumke

7

object named as

Oliver Daumke

1 reference

6 November 2017

Sabine Kupzig

1

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6 November 2017

Delia Deaconescu

2

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6 November 2017

Dalila Bouyoucef

3

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6 November 2017

Simon A Walker

4

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6 November 2017

Qing Liu

5

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6 November 2017

Christian L Polte

6

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6 November 2017

Toshimasa Ishizaki

8

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6 November 2017

Peter J Lockyer

9

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6 November 2017

language of work or name

English

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publication date

23 January 2006

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Journal of Biological Chemistry

6 November 2017

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6 November 2017

281

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6 November 2017

15

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6 November 2017

9891-9900

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describes a project that uses

6 November 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1904491/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.

27 May 2018

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A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

27 May 2018

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A genetic screen for candidate tumor suppressors identifies REST

27 May 2018

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The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade.

27 May 2018

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Linking Rap to cell adhesion

27 May 2018

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SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation

27 May 2018

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GAP control: regulating the regulators of small GTPases

27 May 2018

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The GTPase-activating protein Rap1GAP uses a catalytic asparagine

27 May 2018

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Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations

27 May 2018

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Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II

27 May 2018

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Rap1 GTPase: Functions, Regulation, and Malignancy

27 May 2018

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The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain

27 May 2018

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Does Rap1 deserve a bad Rap?

27 May 2018

1 reference

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Ras proteins: different signals from different locations

27 May 2018

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DOCK4, a GTPase activator, is disrupted during tumorigenesis

27 May 2018

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GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila

27 May 2018

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Cellular functions of the Rap1 GTP-binding protein: a pattern emerges

27 May 2018

1 reference

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Ras and Rap control AMPA receptor trafficking during synaptic plasticity

27 May 2018

1 reference

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Integration of calcium and Ras signalling.

27 May 2018

1 reference

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GTPase activating proteins: critical regulators of intracellular signaling

27 May 2018

1 reference

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CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway

27 May 2018

1 reference

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Rap1 signalling: adhering to new models

27 May 2018

1 reference

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The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain

27 May 2018

1 reference

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GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association.

27 May 2018

1 reference

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Understanding Ras: 'it ain't over 'til it's over'.

27 May 2018

1 reference

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Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo

27 May 2018

1 reference

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Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog

27 May 2018

1 reference

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Structural and functional analysis of the putative inositol 1,3,4, 5-tetrakisphosphate receptors GAP1(IP4BP) and GAP1(m).

27 May 2018

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A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II

27 May 2018

1 reference

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SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

27 May 2018

1 reference

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Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

27 May 2018

1 reference

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The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

27 May 2018

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Rapid Ca2+-mediated activation of Rap1 in human platelets

27 May 2018

1 reference

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Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras

27 May 2018

1 reference

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A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions

27 May 2018

1 reference

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Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Autoinhibition of p50 Rho GTPase-activating protein (GAP) is released by prenylated small GTPases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Rap-specific GTPase activating protein follows an alternative mechanism

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Bridging the GAP in inositol 1,3,4,5-tetrakisphosphate signalling.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904491

Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16431904

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16431904

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M512802200

1 reference

6 November 2017

1 reference

6 November 2017

PubMed publication ID

16431904

1 reference