High-throughput sequencing of the melanoma genome (Q42773490)

7 November 2017

title

High-throughput sequencing of the melanoma genome (English)

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high-throughput sequencing

7 November 2017

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3

Janet Kelso

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7 November 2017

Manfred Kunz

1

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7 November 2017

Michael Dannemann

series ordinal

2

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7 November 2017

publication date

22 November 2012

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7 November 2017

published in

Experimental Dermatology

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7 November 2017

volume

22

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7 November 2017

issue

1

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7 November 2017

page(s)

10-17

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7 November 2017

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Distinct sets of genetic alterations in melanoma

21 January 2018

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Analysis of the genome to personalize therapy for melanoma

21 January 2018

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

21 January 2018

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Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

21 January 2018

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

21 January 2018

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Targeting mutant BRAF in melanoma: current status and future development of combination therapy strategies

21 January 2018

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

21 January 2018

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 January 2018

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Reactivation of mitogen-activated protein kinase (MAPK) pathway by FGF receptor 3 (FGFR3)/Ras mediates resistance to vemurafenib in human B-RAF V600E mutant melanoma

21 January 2018

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KIT as a therapeutic target in metastatic melanoma

21 January 2018

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Melanoma genetics and the development of rational therapeutics

21 January 2018

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

21 January 2018

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Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations

21 January 2018

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Next-generation DNA sequencing methods

21 January 2018

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Sequencing technologies - the next generation

21 January 2018

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Next-generation sequencing technologies and fragment assembly algorithms

21 January 2018

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High-throughput DNA sequencing--concepts and limitations

21 January 2018

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Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

21 January 2018

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BTA, a novel reagent for DNA attachment on glass and efficient generation of solid-phase amplified DNA colonies.

21 January 2018

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Single-molecule DNA sequencing of a viral genome

21 January 2018

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A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning

21 January 2018

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Performance comparison of benchtop high-throughput sequencing platforms

21 January 2018

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Real-time DNA sequencing from single polymerase molecules

21 January 2018

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Oxford Nanopore announcement sets sequencing sector abuzz.

21 January 2018

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Analysis of next-generation genomic data in cancer: accomplishments and challenges

21 January 2018

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A new branch on the tree: next-generation sequencing in the study of cancer evolution.

21 January 2018

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International network of cancer genome projects

21 January 2018

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Advances in understanding cancer genomes through second-generation sequencing

21 January 2018

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Application of second-generation sequencing to cancer genomics

21 January 2018

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Improved base calling for the Illumina Genome Analyzer using machine learning strategies

21 January 2018

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A map of human genome variation from population-scale sequencing

21 January 2018

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How to map billions of short reads onto genomes

21 January 2018

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Cancer genome sequencing: a review

21 January 2018

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Mapping short DNA sequencing reads and calling variants using mapping quality scores

21 January 2018

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Fast and accurate short read alignment with Burrows-Wheeler transform

21 January 2018

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

21 January 2018

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SOAP3: ultra-fast GPU-based parallel alignment tool for short reads

21 January 2018

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SHRiMP: accurate mapping of short color-space reads

21 January 2018

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Detection of splice junctions from paired-end RNA-seq data by SpliceMap.

21 January 2018

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TopHat: discovering splice junctions with RNA-Seq

21 January 2018

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Fast and SNP-tolerant detection of complex variants and splicing in short reads

21 January 2018

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Genotype and SNP calling from next-generation sequencing data

21 January 2018

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A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

21 January 2018

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

21 January 2018

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The Sequence Alignment/Map format and SAMtools

21 January 2018

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Paired-end mapping reveals extensive structural variation in the human genome

21 January 2018

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BreakDancer: an algorithm for high-resolution mapping of genomic structural variation

21 January 2018

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Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 January 2018

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An integrative probabilistic model for identification of structural variation in sequencing data

21 January 2018

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CREST maps somatic structural variation in cancer genomes with base-pair resolution.

21 January 2018

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Challenges in studying genomic structural variant formation mechanisms: the short-read dilemma and beyond

21 January 2018

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Transcriptome sequencing to detect gene fusions in cancer

21 January 2018

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

21 January 2018

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RNA-Seq: a revolutionary tool for transcriptomics

21 January 2018

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

21 January 2018

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Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression

21 January 2018

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Mutations induced by ultraviolet light

21 January 2018

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Integrative analysis of the melanoma transcriptome

21 January 2018

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RECK: a novel suppressor of malignancy linking oncogenic signaling to extracellular matrix remodeling

21 January 2018

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Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

21 January 2018

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Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

21 January 2018

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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

21 January 2018

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Mechanism of activation and inhibition of the HER4/ErbB4 kinase

21 January 2018

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Exome sequencing identifies GRIN2A as frequently mutated in melanoma

21 January 2018

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Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma

21 January 2018

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Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

21 January 2018

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Riluzole enhances ionizing radiation-induced cytotoxicity in human melanoma cells that ectopically express metabotropic glutamate receptor 1 in vitro and in vivo.

21 January 2018

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Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

21 January 2018

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Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma

21 January 2018

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Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

21 January 2018

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Personalized oncology through integrative high-throughput sequencing: a pilot study

21 January 2018

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From genes to drugs: targeted strategies for melanoma

21 January 2018

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Whole genome sequencing of matched primary and metastatic acral melanomas

21 January 2018

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Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt.

21 January 2018

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Constitutive activation of the mitogen-activated protein kinase signaling pathway in acral melanomas

21 January 2018

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Melanotransferrin induces human melanoma SK-Mel-28 cell invasion in vivo

21 January 2018

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RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling

21 January 2018

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Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

21 January 2018

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A landscape of driver mutations in melanoma

21 January 2018

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

21 January 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

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Cancer as an evolutionary and ecological process

21 January 2018

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Recent advances in DNA sequencing methods - general principles of sample preparation

21 January 2018

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Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

21 January 2018

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Development of a next-generation sequencing method for BRCA mutation screening: a comparison between a high-throughput and a benchtop platform

21 January 2018

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How melanomas bypass new therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/EXD.12054

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7 November 2017

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