Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease. (Q42778066)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24009238%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease (English)

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2

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David A Long

16

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20 February 2020

Karen L Price

7

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14

Matthias Kretzler

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20 February 2020

author name string

Cecile Dessapt-Baradez

1

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20 February 2020

Kathryn E White

3

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Jiaqi Pan

4

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20 February 2020

Jennifer L Huang

5

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20 February 2020

Anthea A Hayward

6

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20 February 2020

Maria Kolatsi-Joannou

8

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20 February 2020

Maelle Locatelli

9

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20 February 2020

Marine Diennet

10

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20 February 2020

Zoe Webster

11

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20 February 2020

Sarah J Smillie

12

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20 February 2020

Viji Nair

13

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20 February 2020

Clemens D Cohen

15

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20 February 2020

Luigi Gnudi

17

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20 February 2020

publication date

5 September 2013

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Journal of the American Society of Nephrology

20 February 2020

published in

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20 February 2020

volume

25

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page(s)

33-42

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20 February 2020

issue

1

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Albuminuria is associated with too few glomeruli and too much testosterone

20 February 2020

cites work

1 reference

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Vegfa protects the glomerular microvasculature in diabetes.

27 May 2018

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Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction.

27 May 2018

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Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice

27 May 2018

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Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells

27 May 2018

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Cellular and molecular mechanisms of diabetic glomerulopathy

27 May 2018

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Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes

27 May 2018

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Basic and therapeutic aspects of angiogenesis

27 May 2018

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Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy

27 May 2018

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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

27 May 2018

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Podocyte vascular endothelial growth factor (Vegf₁₆₄) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes.

27 May 2018

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Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling.

27 May 2018

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Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats

27 May 2018

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The clinical significance of hyperfiltration in diabetes

27 May 2018

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Abnormal angiogenesis in diabetic nephropathy.

27 May 2018

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Angiopoietin-1 alters microvascular permeability coefficients in vivo via modification of endothelial glycocalyx

27 May 2018

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

27 May 2018

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Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

27 May 2018

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Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase

27 May 2018

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Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice

27 May 2018

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

27 May 2018

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27 May 2018

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Glomerular endothelial glycocalyx constitutes a barrier to protein permeability

27 May 2018

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Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease

27 May 2018

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Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes

27 May 2018

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27 May 2018

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Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes

27 May 2018

1 reference

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Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy.

27 May 2018

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COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity

27 May 2018

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Angiogenic actions of angiopoietin-1 require endothelium-derived nitric oxide

27 May 2018

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Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

27 May 2018

1 reference

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A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

27 May 2018

1 reference

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Angiopoietin-1 protects the adult vasculature against plasma leakage.

27 May 2018

1 reference

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Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis

27 May 2018

1 reference

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Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.

27 May 2018

1 reference

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The glomerular endothelial cell coat is essential for glomerular filtration.

16 August 2018

1 reference

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Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease.

16 August 2018

1 reference

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Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice

16 August 2018

1 reference

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Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes.

16 August 2018

1 reference

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Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871771

Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871771

Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871771

Electron microscopic evaluation of the endothelial surface layer of glomerular capillaries.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871771

Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus

16 August 2018

1 reference

12 December 2020

Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice

1 reference

12 December 2020

Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia

1 reference

12 December 2020

Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor

1 reference

12 December 2020

Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes

1 reference

12 December 2020

Coexpression of neuropilin-1, Flk1, and VEGF(164) in developing and mature mouse kidney glomeruli

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2012121218

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24009238%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24009238%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24009238%20AND%20SRC:MED&resulttype=core&format=json