Suppression of beta cell energy metabolism and insulin release by PGC-1alpha (Q42799597)

7 November 2017

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha (English)

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7 November 2017

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7 November 2017

Jude T Deeney

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Bruce Spiegelman

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object named as

Bruce M Spiegelman

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Per-Olof Berggren

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7 November 2017

Christopher B Newgard

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object named as

Christopher B Newgard

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7 November 2017

J Cliff Yoon

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7 November 2017

Gang Xu

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7 November 2017

Shao-Nian Yang

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7 November 2017

James Rhee

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7 November 2017

Pere Puigserver

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7 November 2017

Adah R Levens

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7 November 2017

Ruojing Yang

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7 November 2017

Chen-Yu Zhang

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7 November 2017

Bradford B Lowell

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7 November 2017

Gordon Weir

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7 November 2017

language of work or name

English

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publication date

1 July 2003

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7 November 2017

11

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inferred from page(s)

published in

Developmental Cell

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7 November 2017

5

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7 November 2017

1

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7 November 2017

73-83

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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes

7 November 2017

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Diabetes mellitus and genetically programmed defects in beta-cell function

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Metabolic control of beta-cell function

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Superoxide activates mitochondrial uncoupling proteins

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Insulin resistance and beta-cell dysfunction as therapeutic targets in type 2 diabetes

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Pancreatic islet mitochondrial glycerophosphate dehydrogenase deficiency in two animal models of non-insulin-dependent diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Glucose-6-phosphatase in the insulin secreting cell line INS-1.

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetes

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms.

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Glucose cycling in islets from healthy and diabetic rats

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Metabolic coupling factors in pancreatic beta-cell signal transduction

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes.

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Luminometric assays of ATP, phosphocreatine, and creatine for estimation of free ADP and free AMP

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Dissecting the transcriptional network of pancreatic islets during development and differentiation

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https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Are metabolic oscillations responsible for normal oscillatory insulin secretion?

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Adenovirus-mediated expression of the catalytic subunit of glucose-6-phosphatase in INS-1 cells. Effects on glucose cycling, glucose usage, and insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2803%2900170-9

7 January 2021

10.1016/S1534-5807(03)00170-9

Identifiers

DOI

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7 November 2017

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