Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling (Q42811147)

7 November 2017

title

Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling (English)

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7 November 2017

4

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7 November 2017

Qi-Wen Fan

1

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7 November 2017

Chao Zhang

series ordinal

2

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7 November 2017

Kevan M Shokat

series ordinal

3

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7 November 2017

language of work or name

English

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publication date

1 August 2002

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7 November 2017

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7 November 2017

volume

12

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7 November 2017

issue

16

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7 November 2017

page(s)

1386-1394

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Epidermal growth factor-related peptides and their receptors in human malignancies

7 November 2017

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Epidermal growth factor receptor signaling

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Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

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Transient deactivation of ERK signalling is sufficient for stable entry into G0 in primary avian fibroblasts

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Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity

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7 January 2021

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7 January 2021

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7 January 2021

Acquisition of inhibitor-sensitive protein kinases through protein design

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7 January 2021

Orientation of the v-erb-B gene product in the plasma membrane

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7 January 2021

10.1016/S0960-9822(02)01070-9

Identifiers

DOI

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7 November 2017

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