Identification of enhanced serine kinase activity in insulin resistance (Q42817429)

7 November 2017

Identification of enhanced serine kinase activity in insulin resistance (English)

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7 November 2017

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Qiao LY

1

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7 November 2017

Goldberg JL

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2

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7 November 2017

Russell JC

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3

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7 November 2017

Sun XJ

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4

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7 November 2017

language of work or name

English

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publication date

1 April 1999

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

274

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7 November 2017

15

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7 November 2017

10625-10632

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

7 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

The IRS-signalling system in insulin and cytokine action

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

The insulin signalling system and the IRS proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Cross-talk between the platelet-derived growth factor and the insulin signaling pathways in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Abnormal insulin and glucose metabolism in the JCR:LA-corpulent rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Development of insulin resistance in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

14-3-3beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3'-kinase activity in 3T3L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.15.10625

21 January 2018

Identifiers

DOI

10.1074/JBC.274.15.10625

1 reference

7 November 2017

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