Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein (Q42826741)

8 November 2017

title

Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein (English)

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8 November 2017

2

Frederic G Barr

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8 November 2017

Shujuan J Xia

1

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8 November 2017

language of work or name

English

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publication date

1 September 2004

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8 November 2017

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8 November 2017

volume

23

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8 November 2017

issue

41

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8 November 2017

page(s)

6864-6871

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Molecular genetics and pathogenesis of rhabdomyosarcoma

8 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207850

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

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Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

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Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

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Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

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Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma

21 January 2018

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Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

21 January 2018

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Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207850

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207850

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

21 January 2018

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Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

21 January 2018

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Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas

21 January 2018

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7 January 2021

Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207850

7 January 2021

Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study

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7 January 2021

Early evolutionary origin of major homeodomain sequence classes

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207850

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Dimensions Publication ID

8 November 2017

1037359905

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