Determination of nutlin-3a in murine plasma by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). (Q42925338)

11 November 2017

Determination of nutlin-3a in murine plasma by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). (English)

1 reference

11 November 2017

electrospray ionization

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author name string

Feng Bai

1

1 reference

11 November 2017

Fangyi Zhu

2

1 reference

11 November 2017

Michael Tagen

3

1 reference

11 November 2017

Laura Miller

4

1 reference

11 November 2017

Thandranese S Owens

5

1 reference

11 November 2017

Jeremy Mallari

6

1 reference

11 November 2017

Edward Derrick

7

1 reference

11 November 2017

Fan Zhang

8

1 reference

11 November 2017

Clinton F Stewart

9

1 reference

11 November 2017

30 October 2009

1 reference

Journal of Pharmaceutical and Biomedical Analysis

11 November 2017

1 reference

11 November 2017

51

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11 November 2017

4

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11 November 2017

915-920

1 reference

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Targeting MDM2 and MDMX in retinoblastoma

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Identification of an aberrantly spliced form of HDMX in human tumors: a new mechanism for HDM2 stabilization

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

MDM2 is a central node in the p53 pathway: 12 years and counting

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Ion suppression in mass spectrometry

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Functions of the MDM2 oncoprotein

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Database of p53 gene somatic mutations in human tumors and cell lines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Determination of ketoconazole in human plasma by high-performance liquid chromatography-tandem mass spectrometry

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814893

Stability assessment of ketoconazole in aqueous formulations

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19931997

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JPBA.2009.10.016

1 reference

11 November 2017

1 reference

11 November 2017

PubMed publication ID

19931997

1 reference