Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. (Q42934893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19875981%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction (English)

1 reference

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11 February 2020

4

1 reference

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11 February 2020

author name string

Marina L Kozak

1

1 reference

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11 February 2020

Alejandro Chavez

2

1 reference

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11 February 2020

Weiwei Dang

3

1 reference

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11 February 2020

Annie Ashok

5

1 reference

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11 February 2020

Xiaoge Guo

6

1 reference

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11 February 2020

F Brad Johnson

7

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11 February 2020

language of work or name

English

0 references

publication date

29 October 2009

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11 February 2020

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11 February 2020

volume

29

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11 February 2020

issue

1

1 reference

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11 February 2020

page(s)

158-170

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A two-step model for senescence triggered by a single critically short telomere

11 February 2020

cites work

1 reference

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Telomeres do the (un)twist: helicase actions at chromosome termini

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Structural and Functional Studies of the Rap1 C-Terminus Reveal Novel Separation-of-Function Mutants

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Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

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Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin

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Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiae

27 May 2018

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Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3.

27 May 2018

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MYST opportunities for growth control: yeast genes illuminate human cancer gene functions

27 May 2018

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Break-induced replication and telomerase-independent telomere maintenance require Pol32.

27 May 2018

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Evidence that a RecQ helicase slows senescence by resolving recombining telomeres

27 May 2018

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Interplay of replication checkpoints and repair proteins at stalled replication forks

27 May 2018

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The epigenetic regulation of mammalian telomeres

27 May 2018

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Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

27 May 2018

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Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

27 May 2018

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Sir3 C-terminal domain involvement in the initiation and spreading of heterochromatin.

27 May 2018

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Histone H4-K16 acetylation controls chromatin structure and protein interactions

27 May 2018

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Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence

27 May 2018

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Sir2 blocks extreme life-span extension.

27 May 2018

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Involvement of human MOF in ATM function

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants

27 May 2018

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Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants

27 May 2018

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27 May 2018

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Barrier proteins remodel and modify chromatin to restrict silenced domains

27 May 2018

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Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing

27 May 2018

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Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae

27 May 2018

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Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone

27 May 2018

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Short telomeres induce a DNA damage response in Saccharomyces cerevisiae

27 May 2018

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Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex

27 May 2018

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Homologous recombination resolution defect in werner syndrome

27 May 2018

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MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae

27 May 2018

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Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae.

27 May 2018

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The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae

27 May 2018

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Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast

27 May 2018

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Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation

27 May 2018

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The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae

27 May 2018

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The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1

27 May 2018

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Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast.

27 May 2018

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The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase

27 May 2018

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Replication and recombination intersect

27 May 2018

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

27 May 2018

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Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

27 May 2018

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

27 May 2018

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SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae

27 May 2018

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Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae

27 May 2018

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Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

27 May 2018

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Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths.

27 May 2018

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Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

27 May 2018

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MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

27 May 2018

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RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase

27 May 2018

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Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

27 May 2018

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

27 May 2018

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Molecular model for telomeric heterochromatin in yeast

27 May 2018

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SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

27 May 2018

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The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

27 May 2018

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Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

27 May 2018

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Spreading of transcriptional repressor SIR3 from telomeric heterochromatin

27 May 2018

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Tethered Sir3p nucleates silencing at telomeres and internal loci in Saccharomyces cerevisiae

27 May 2018

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

27 May 2018

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An alternative pathway for yeast telomere maintenance rescues est1- senescence

27 May 2018

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SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

27 May 2018

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Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.

27 May 2018

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Extra telomeres, but not internal tracts of telomeric DNA, reduce transcriptional repression at Saccharomyces telomeres

27 May 2018

1 reference

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Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

27 May 2018

1 reference

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TLC1: template RNA component of Saccharomyces cerevisiae telomerase

27 May 2018

1 reference

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A mutant with a defect in telomere elongation leads to senescence in yeast

27 May 2018

1 reference

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Saccharomyces telomeres assume a non-nucleosomal chromatin structure

27 May 2018

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The DNA damage response at eroded telomeres and tethering to the nuclear pore complex.

27 May 2018

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Insights into the impact of histone acetylation and methylation on Sir protein recruitment, spreading, and silencing in Saccharomyces cerevisiae

16 August 2018

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SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae

16 August 2018

1 reference

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Characterization of the yeast trimeric-SAS acetyltransferase complex

16 August 2018

1 reference

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Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Regulation of subtelomeric silencing during stress response.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Telomere position effect in human cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808364

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

16 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.314

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.314

Single-Cell Observations Reveal Intermediate Transcriptional Silencing States

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.314

Semi-conservative DNA replication through telomeres requires Taz1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.314

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast

21 January 2018

1 reference

12 December 2020

Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly

1 reference

12 December 2020

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

12 December 2020

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.314

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19875981%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19875981%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19875981

1 reference