Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements. (Q42937057)

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10 February 2020

title

Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements (English)

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G protein-coupled receptor

10 February 2020

main subject

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11

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10 February 2020

Nicola J Smith

12

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10 February 2020

author name string

Ralf Schröder

1

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10 February 2020

Nicole Janssen

2

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10 February 2020

Johannes Schmidt

3

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10 February 2020

Anna Kebig

4

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10 February 2020

Nicole Merten

5

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10 February 2020

Stephanie Hennen

6

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10 February 2020

Anke Müller

7

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Stefanie Blättermann

8

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10 February 2020

Marion Mohr-Andrä

9

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Sabine Zahn

10

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10 February 2020

Jesús Gomeza

13

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10 February 2020

Christel Drewke

14

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10 February 2020

Graeme Milligan

15

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10 February 2020

Klaus Mohr

16

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10 February 2020

Evi Kostenis

17

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10 February 2020

publication date

15 August 2010

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10 February 2020

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10 February 2020

volume

28

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issue

9

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page(s)

943-949

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https://scigraph.springernature.com/pub.10.1038/nbt.1671

10 February 2020

exact match

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cites work

Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

1 reference

12 December 2020

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

1 reference

12 December 2020

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

1 reference

12 December 2020

Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.

1 reference

12 December 2020

Optical biosensor differentiates signaling of endogenous PAR1 and PAR2 in A431 cells.

1 reference

12 December 2020

Receptors coupled to heterotrimeric G proteins of the G12 family

1 reference

12 December 2020

7TM pharmacology measured by label-free: a holistic approach to cell signalling

1 reference

12 December 2020

How many drug targets are there?

1 reference

12 December 2020

Comparing label-free biosensors for pharmacological screening with cell-based functional assays.

1 reference

12 December 2020

The evasive nature of drug efficacy: implications for drug discovery

1 reference

12 December 2020

cAMP detection methods in HTS: selecting the best from the rest

1 reference

12 December 2020

Functional G protein-coupled receptor assays for primary and secondary screening

1 reference

12 December 2020

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

1 reference

12 December 2020

High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay

1 reference

12 December 2020

Evaluation of dynamic mass redistribution technology for pharmacological studies of recombinant and endogenously expressed g protein-coupled receptors

1 reference

12 December 2020

Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist

1 reference

12 December 2020

Generation of cortical neurons from mouse embryonic stem cells

1 reference

12 December 2020

Oligomerization of wild type and nonfunctional mutant angiotensin II type I receptors inhibits galphaq protein signaling but not ERK activation.

1 reference

12 December 2020

The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation

1 reference

12 December 2020

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

12 December 2020

The orphan receptor GPR55 is a novel cannabinoid receptor

1 reference

12 December 2020

Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

1 reference

12 December 2020

Beta galactosidase complementation: a cell-based luminescent assay platform for drug discovery

1 reference

12 December 2020

A novel Galphaq/11-selective inhibitor

1 reference

12 December 2020

Enhanced selectivity screening of GPCR ligands using a label-free cell based assay technology

1 reference

12 December 2020

m3 Muscarinic receptor-induced and Gi-mediated heterologous potentiation of phospholipase C stimulation: role of phosphoinositide synthesis

1 reference

12 December 2020

Cellular assays as portals to seven-transmembrane receptor-based drug discovery

1 reference

12 December 2020

Effects of prostaglandin E1 on human keratinocytes and dermal fibroblasts: a possible mechanism for the healing of skin ulcers

1 reference

12 December 2020

Beta-arrestin-biased ligands at seven-transmembrane receptors

1 reference

12 December 2020

GPR55 ligands promote receptor coupling to multiple signalling pathways

1 reference

12 December 2020

Resonant waveguide grating biosensor for living cell sensing.

1 reference

12 December 2020

Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance

1 reference

12 December 2020

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

1 reference

12 December 2020

A 100K well screen for a muscarinic receptor using the Epic label-free system--a reflection on the benefits of the label-free approach to screening seven-transmembrane receptors

1 reference

12 December 2020

Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2

1 reference

12 December 2020

Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells.

1 reference

12 December 2020

beta-arrestins: traffic cops of cell signaling

1 reference

12 December 2020

The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1

1 reference

12 December 2020

Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates.

1 reference

12 December 2020

The enigmatic pharmacology of GPR55

1 reference

12 December 2020

The genetic design of signaling cascades to record receptor activation

1 reference

12 December 2020

Live-cell imaging of cAMP dynamics

1 reference

12 December 2020

Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation

1 reference

12 December 2020

G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors

1 reference

12 December 2020

Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells

1 reference

12 December 2020

Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox

1 reference

12 December 2020

Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent

1 reference

12 December 2020

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

12 December 2020

Impedance-based cellular assay technologies: recent advances, future promise

1 reference

12 December 2020

Alternative splicing in the N-terminal extracellular domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor modulates receptor selectivity and relative potencies of PACAP-27 and PACAP-38 in phospholipase C activation

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT.1671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20711173%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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