The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion. (Q43055167)

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3 February 2020

title

The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion (English)

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3 February 2020

10

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Christophe Magnan

7

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3 February 2020

Fatima Bosch

13

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3 February 2020

author name string

P Lebrun

1

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3 February 2020

E Cognard

2

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P Gontard

3

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R Bellon-Paul

4

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3 February 2020

C Filloux

5

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M F Berthault

6

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J Ruberte

8

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M Luppo

9

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N Pachera

11

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A Herchuelz

12

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E Van Obberghen

14

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publication date

25 May 2010

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3 February 2020

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3 February 2020

volume

53

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issue

9

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3 February 2020

page(s)

1935-1946

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https://scigraph.springernature.com/pub.10.1007/s00125-010-1786-9

3 February 2020

exact match

0 references

cites work

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

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Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

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The stimulus--secretion coupling 4-methyl-2-oxopentanoate-induced insulin release

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Endoplasmic reticulum Ca2+ is important for the proteolytic processing and intracellular transport of proinsulin in the pancreatic beta-cell

21 January 2018

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The coupling of metabolic to secretory events in pancreatic islets: inhibition by 2-cyclohexene-1-one of the secretory response to cyclic AMP and cytochalasin B

21 January 2018

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12 December 2020

Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic beta cells to tumor necrosis factor

1 reference

12 December 2020

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

1 reference

12 December 2020

Reduced Bone Mineral Density in SOCS-2-Deficient Mice

1 reference

12 December 2020

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

1 reference

12 December 2020

Hexose metabolism in pancreatic islets: the Pasteur effect

1 reference

12 December 2020

IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

1 reference

12 December 2020

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

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12 December 2020

The role for endoplasmic reticulum stress in diabetes mellitus

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12 December 2020

Regulation of insulin secretion: a matter of phase control and amplitude modulation

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12 December 2020

Regulation of prohormone convertase 1 (PC1) by gp130-related cytokines

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12 December 2020

Regulation of beta-cell mass by hormones and growth factors

1 reference

12 December 2020

Suppressor of cytokine signalling-2 and epidermal growth factor regulate neurite outgrowth of cortical neurons

1 reference

12 December 2020

Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.

1 reference

12 December 2020

Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules

1 reference

12 December 2020

Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity

1 reference

12 December 2020

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

1 reference

12 December 2020

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling

1 reference

12 December 2020

Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion

1 reference

12 December 2020

Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult Rats

1 reference

12 December 2020

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

1 reference

12 December 2020

The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells.

1 reference

12 December 2020

Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the Japanese

1 reference

12 December 2020

Comparative analysis of CNS populations in knockout mice with altered growth hormone responsiveness

1 reference

12 December 2020

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

1 reference

12 December 2020

Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signaling

1 reference

12 December 2020

Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

1 reference

12 December 2020

Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent

1 reference

12 December 2020

Ca2+ microdomains and the control of insulin secretion

1 reference

12 December 2020

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

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12 December 2020

Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array

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12 December 2020

gamma-Interferon signaling in pancreatic beta-cells is persistent but can be terminated by overexpression of suppressor of cytokine signaling-1

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12 December 2020

SOCS proteins, cytokine signalling and immune regulation

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12 December 2020

Linoleic acid induces Ca2+-induced inactivation of voltage-dependent Ca2+ currents in rat pancreatic beta-cells

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12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

12 December 2020

Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells

1 reference

12 December 2020

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

1 reference

12 December 2020

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

1 reference

12 December 2020

The effect of suppressor of cytokine signaling 3 on GH signaling in beta-cells

1 reference

12 December 2020

SOCS2 negatively regulates growth hormone action in vitro and in vivo

1 reference

12 December 2020

Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism

1 reference

12 December 2020

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

1 reference

12 December 2020

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

1 reference

12 December 2020

Suppressor of cytokine signaling-2 limits intestinal growth and enterotrophic actions of IGF-I in vivo

1 reference

12 December 2020

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

1 reference

12 December 2020

3T3-L1 adipocytes induce dysfunction of MIN6 insulin-secreting cells via multiple pathways mediated by secretory factors in a co-culture system.

1 reference

12 December 2020

Gigantism in mice lacking suppressor of cytokine signalling-2

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12 December 2020

Growth factor control of pancreatic islet regeneration and function

1 reference

12 December 2020

Contribution of Na/Ca exchange to Ca2+ outflow and entry in the rat pancreatic beta-cell: studies with antisense oligonucleotides.

1 reference

12 December 2020

SOCS-3 is an insulin-induced negative regulator of insulin signaling

1 reference

12 December 2020