Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people (Q43085753)

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scientific article published on 26 April 2010

Language	Label	Description	Also known as
English	Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people	scientific article published on 26 April 2010

Statements

scholarly article

1 reference

Europe PubMed Central

13 November 2017

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Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people (English)

1 reference

Europe PubMed Central

13 November 2017

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2

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Europe PubMed Central

13 November 2017

Torben Jørgensen

3

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Europe PubMed Central

13 November 2017

object named as

T Hansen

6

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Oluf Borbye Pedersen

object named as

O Pedersen

7

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Knut Borch-Johnsen

4

object named as

K Borch-Johnsen

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Europe PubMed Central

13 November 2017

author name string

T W Boesgaard

1

1 reference

Europe PubMed Central

13 November 2017

Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC)

5

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Europe PubMed Central

13 November 2017

publication date

26 April 2010

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Europe PubMed Central

13 November 2017

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Europe PubMed Central

13 November 2017

53

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Europe PubMed Central

13 November 2017

8

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Europe PubMed Central

13 November 2017

1647-1655

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Europe PubMed Central

13 November 2017

https://scigraph.springernature.com/pub.10.1007/s00125-010-1753-5

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The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association studies in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variants in MTNR1B influence fasting glucose levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathomechanisms of type 2 diabetes genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose tolerance and insulin release, a mathematical approach I. Assay of the beta-cell response after oral glucose loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parental origin of sequence variants associated with complex diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/20419449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-010-1753-5

1 reference

Europe PubMed Central

13 November 2017

1 reference

Europe PubMed Central

13 November 2017

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