mTOR, AMPK, and GCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat. (Q43279501)

18 November 2017

mTOR, AMPK, and GCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat. (English)

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18 November 2017

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Dalila Azzout-Marniche

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Dalila Azzout-Marniche

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author name string

Nattida Chotechuang

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18 November 2017

Cécile Bos

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18 November 2017

Catherine Chaumontet

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18 November 2017

Nicolas Gausserès

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18 November 2017

Tatiana Steiler

6

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18 November 2017

Claire Gaudichon

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18 November 2017

Daniel Tomé

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18 November 2017

8 September 2009

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American Journal of Physiology - Endocrinology and Metabolism

18 November 2017

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18 November 2017

297

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18 November 2017

E1313-23

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18 November 2017

6

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Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

18 November 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Liver glyconeogenesis: a pathway to cope with postprandial amino acid excess in high-protein fed rats?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

A high-protein diet enhances satiety without conditioned taste aversion in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

High-protein diets differentially modulate protein content and protein synthesis in visceral and peripheral tissues in rats.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Gene-specific regulation by general translation factors

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

GCN2 whets the appetite for amino acids

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Nutrient signalling in the regulation of human muscle protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Role of amino acids in insulin signaling in adipocytes and their potential to decrease insulin resistance of adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase-Dependent Regulation of the Orphan Nuclear Receptor SHP

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

TSC2: filling the GAP in the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Novel role of the small GTPase Rheb: its implication in endocytic pathway independent of the activation of mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

mTOR signaling: RAG GTPases transmit the amino acid signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Human VPS34 and p150 are Rab7 Interacting Partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Dietary protein intake affects albumin fractional synthesis rate in younger and older adults equally

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.91000.2008

10.1152/AJPENDO.91000.2008

21 January 2018

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DOI

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18 November 2017

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