Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana (Q43610414)

25 November 2017

title

Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana (English)

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25 November 2017

Leishmania mexicana

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3

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5

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Alves LC

1

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25 November 2017

St Hilaire PM

2

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Sanderson SJ

4

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Coombs GH

6

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25 November 2017

Juliano L

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25 November 2017

Juliano MA

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25 November 2017

publication date

1 April 2001

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Molecular and Biochemical Parasitology

25 November 2017

published in

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25 November 2017

volume

114

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25 November 2017

issue

1

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25 November 2017

page(s)

81-88

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Proteinases of Leishmania mexicana and other flagellate protozoa

25 November 2017

cites work

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Characterisation of three groups of cysteine proteinases in the amastigotes of Leishmania mexicana mexicana

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Stage-specific proteinases of Leishmania mexicana mexicana promastigotes

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7 January 2021

Expression of Cysteine Proteinases by Metacyclic Promastigotes of Leishmania mexicana

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7 January 2021

The multiple cpb cysteine proteinase genes of Leishmania mexicana encode isoenzymes that differ in their stage regulation and substrate preferences

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7 January 2021

Characterization of a multi-copy gene for a major stage-specific cysteine proteinase of Leishmania mexicana

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7 January 2021

Multiple high activity cysteine proteases of Leishmania mexicana are encoded by the Imcpb gene array

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7 January 2021

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

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7 January 2021

Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using the polymerase chain reaction

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7 January 2021

Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids

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7 January 2021

The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes

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7 January 2021

Structural and functional identification of GP57/51 antigen of Trypanosoma cruzi as a cysteine proteinase

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7 January 2021

A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual C-terminal extension

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7 January 2021

Cysteine protease inhibitors as chemotherapy: lessons from a parasite target

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Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro

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7 January 2021

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

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7 January 2021

Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction

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7 January 2021

Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action

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Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

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Recent advances in identifying and validating drug targets in trypanosomes and leishmanias.

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7 January 2021

Expression and characterization of a recombinant cysteine proteinase of Leishmania mexicana.

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7 January 2021

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

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7 January 2021

Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases

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7 January 2021

Potent slow-binding inhibition of cathepsin B by its propeptide

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7 January 2021

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

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7 January 2021

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

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7 January 2021

Inhibition of cathepsin B by its propeptide: use of overlapping peptides to identify a critical segment

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7 January 2021

Inhibition of trypanosomal cysteine proteinases by their propeptides.

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7 January 2021

The propeptide of Fasciola hepatica cathepsin L is a potent and selective inhibitor of the mature enzyme

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7 January 2021

Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.

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7 January 2021

Intramolecularly quenched fluorogenic tetrapeptide substrates for tissue and plasma kallikreins.

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7 January 2021

Intramolecularly quenched fluorogenic peptide substrates for human renin.

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7 January 2021

Temperature-dependent substrate inhibition of the cysteine proteinase (GP57/51) from Trypanosoma cruzi

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7 January 2021

Statistical estimations in enzyme kinetics

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7 January 2021

Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin

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7 January 2021

Proregion structure of members of the papain superfamily. Mode of inhibition of enzymatic activity

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7 January 2021

The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft

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7 January 2021

10.1016/S0166-6851(01)00239-0

Identifiers

DOI

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25 November 2017

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