microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors (Q43703662)

26 November 2017

microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors (English)

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26 November 2017

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H A Katus

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A Geisler

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A Jungmann

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J Kurreck

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W Poller

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R Vetter

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H Fechner

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O J Müller

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4 November 2010

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199-209

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https://scigraph.springernature.com/pub.10.1038/gt.2010.141

26 November 2017

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Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

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Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

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Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy

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Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

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Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo

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Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.

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A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

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Tissue specific promoters improve specificity of AAV9 mediated transgene expression following intra-vascular gene delivery in neonatal mice.

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Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability

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Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells

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miR-122a-Regulated Expression of a Suicide Gene Prevents Hepatotoxicity Without Altering Antitumor Effects in Suicide Gene Therapy

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siRNAs can function as miRNAs

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MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

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MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths

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Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban

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Clades of Adeno-associated viruses are widely disseminated in human tissues.

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Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers

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Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

21 January 2018

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miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.141

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GT.2010.141

1 reference

Dimensions Publication ID

26 November 2017

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