Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. (Q43833728)

From Wikidata

Jump to navigation Jump to search

scientific article published in January 2002

Language	Label	Description	Also known as
English	Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.	scientific article published in January 2002

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

Charles A Harris

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Mohanish Deshmukh

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Brian Tsui-Pierchala

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Anna C Maroney

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Eugene M Johnson

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

language of work or name

0 references

publication date

1 January 2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

22

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

103-113

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical and biochemical studies of GLUT4 in rat skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death during development of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Techniques in the tissue culture of rat sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporter proteins in brain: delivery of glucose to neurons and glia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756493

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-01-00103.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11756493%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43833728&oldid=2103742328"