Regulation of the mitogen-activated protein kinase signaling pathway by SHP2. (Q43847045)

27 November 2017

Regulation of the mitogen-activated protein kinase signaling pathway by SHP2. (English)

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27 November 2017

5

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27 November 2017

Jess M Cunnick

1

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27 November 2017

Songshu Meng

2

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27 November 2017

Yuan Ren

3

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27 November 2017

Caroline Desponts

4

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27 November 2017

Julie Y Djeu

6

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27 November 2017

Jie Wu

7

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27 November 2017

language of work or name

English

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publication date

4 January 2002

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Journal of Biological Chemistry

27 November 2017

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27 November 2017

277

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27 November 2017

11

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27 November 2017

9498-9504

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Cell signaling by receptor tyrosine kinases

27 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Combinatorial control of the specificity of protein tyrosine phosphatases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Crystal structure of the tyrosine phosphatase SHP-2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110547200

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

Mammalian MAP kinase signalling cascades

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110547200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110547200

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27 November 2017

1 reference