Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer (Q44068250)

29 November 2017

Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer (English)

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29 November 2017

Vito Turk

1

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29 November 2017

Boris Turk

2

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29 November 2017

Gregor Guncar

3

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29 November 2017

Dusan Turk

4

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29 November 2017

Janko Kos

5

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29 November 2017

1 January 2002

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Advances in Enzyme Regulation

29 November 2017

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29 November 2017

42

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29 November 2017

285-303

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

29 November 2017

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7 January 2021

A fragment of the major histocompatibility complex class II-associated p41 invariant chain inhibits cruzipain, the major cysteine proteinase from Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Intracellular proteases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Friends and relations of the cystatin superfamily--new members and their evolution

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Endosomal proteolysis and MHC class II function

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

The residual pro-part of cathepsin C fulfills the criteria required for an intramolecular chaperone in folding and stabilizing the human proenzyme

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Interaction of cystatin C variants with papain and human cathepsins B, H and L

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Oligomeric structure and substrate induced inhibition of human cathepsin C

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cancer. Proteases--invasion and more

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Expression of cathepsins B and S in the progression of prostate carcinoma

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Potent slow-binding inhibition of cathepsin B by its propeptide

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Potency and selectivity of inhibition of cathepsin K, L and S by their respective propeptides

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lymphoid monoclonal antibodies reactive with lung tumors. Diagnostic applications

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Participation of cathepsin L on bone resorption

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Unraveling the role of proteases in cancer

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Saxiphilin, a saxitoxin-binding protein with two thyroglobulin type 1 domains, is an inhibitor of papain-like cysteine proteinases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Thyroglobulin type-1 domains in equistatin inhibit both papain-like cysteine proteinases and cathepsin D.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

The p41 isoform of invariant chain is a chaperone for cathepsin L

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of human cathepsin K complexed with a potent inhibitor

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of human cathepsin S.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Human cathepsin X: A cysteine protease with unique carboxypeptidase activity

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Inhibition of carcinoma cell invasion and liver metastases formation by the cysteine proteinase inhibitor E-64

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

MHC class II restricted antigen presentation

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Characterization by spectroscopic, kinetic and equilibrium methods of the interaction between recombinant human cystatin A (stefin A) and cysteine proteinases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin S activity regulates antigen presentation and immunity

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

On the size of the active site in proteases. I. Papain

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Antigen-processing machinery breakdown and tumor growth

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Peptidyl diazomethanes as inhibitors of cysteine and serine proteinases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin S required for normal MHC class II peptide loading and germinal center development

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

The cystatins: Protein inhibitors of cysteine proteinases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Human cathepsin B is a metastable enzyme stabilized by specific ionic interactions associated with the active site

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Acidic pH as a physiological regulator of human cathepsin L activity.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Kinetics of the pH-induced inactivation of human cathepsin L

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Revised definition of substrate binding sites of papain-like cysteine proteases

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

The p41 fragment story

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lysosomal cysteine proteases: facts and opportunities

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lysosomal cysteine proteases: more than scavengers

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Anti-human procathepsin D activation peptide antibodies inhibit breast cancer development

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Fluorometric microassays for the determination of cathepsin L and cathepsin S activities in tissue extracts

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Lack of class II transactivator causes severe deficiency of HLA-DR expression in small cell lung cancer

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Immunochemical localisation of cathepsin S, cathepsin L and MHC class II-associated p41 isoform of invariant chain in human lymph node tissue

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Crystal structure of human osteoclast cathepsin K complex with E-64

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

Cathepsin B/cystatin C complex levels in sera from patients with lung and colorectal cancer.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2801%2900034-6

7 January 2021

10.1016/S0065-2571(01)00034-6

Identifiers

DOI

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29 November 2017

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