Glucose promotes pancreatic islet beta-cell survival through a PI 3-kinase/Akt-signaling pathway (Q44129326)

30 November 2017

Glucose promotes pancreatic islet beta-cell survival through a PI 3-kinase/Akt-signaling pathway (English)

1 reference

30 November 2017

Shanthi Srinivasan

1

1 reference

30 November 2017

Ernesto Bernal-Mizrachi

series ordinal

2

1 reference

30 November 2017

Mitsuru Ohsugi

series ordinal

3

1 reference

30 November 2017

Marshall Alan Permutt

series ordinal

4

1 reference

30 November 2017

1 October 2002

1 reference

American Journal of Physiology - Endocrinology and Metabolism

30 November 2017

1 reference

30 November 2017

283

1 reference

30 November 2017

E784-93

1 reference

30 November 2017

4

1 reference

Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations.

30 November 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Kinetic and pharmacological properties distinguishing three types of calcium currents in chick sensory neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

TNFalpha inhibits insulin's antiapoptotic signaling in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Essential role of phosphoinositide 3-kinase in leptin-induced K(ATP) channel activation in the rat CRI-G1 insulinoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Preparation of single cells from pancreatic islets of adult rat by the use of dispase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Octameric stoichiometry of the KATP channel complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Are there kinetic advantages of GLUT2 in pancreatic glucose sensing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Apoptosis and cell death in neuronal cells: where does Ca2+ fit in?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

Akt is more than just a Bad kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00177.2002

10.1152/AJPENDO.00177.2002

21 January 2018

Identifiers

DOI

1 reference

30 November 2017

1 reference