Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue (Q44175709)

30 November 2017

title

Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue (English)

1 reference

30 November 2017

1 reference

Thomas B Shea

1

1 reference

30 November 2017

Eugene Rogers

2

1 reference

30 November 2017

David Ashline

3

1 reference

30 November 2017

Daniela Ortiz

4

1 reference

30 November 2017

Min-Shyan Sheu

5

1 reference

30 November 2017

language of work or name

1 reference

1 October 2002

1 reference

Free Radical Biology and Medicine

30 November 2017

published in

1 reference

30 November 2017

volume

33

1 reference

30 November 2017

issue

8

1 reference

30 November 2017

page(s)

1115-1120

1 reference

Incorporating biomarkers into clinical drug trials in Alzheimer's disease.

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Neurodegeneration in the central nervous system of apoE-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Expression of apolipoprotein E during nerve degeneration and regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Nerve injury stimulates the secretion of apolipoprotein E by nonneuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Differential gene expression of livers from ApoE deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocysteine and lipid peroxidation in haemodialysis: role of folinic acid and vitamin E.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Effects of alpha-tocopherol and beta-carotene on hepatic lipid peroxidation and blood lipids in rats with dietary iron overload

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Oxidative stress and antioxidant status in mouse liver: effects of dietary lipid, vitamin E and iron

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Efficacy of vitamin E, phosphatidyl choline, and pyruvate on buffering neuronal degeneration and oxidative stress in cultured cortical neurons and in central nervous tissue of apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Brains of aged apolipoprotein E-deficient mice have increased levels of F2-isoprostanes, in vivo markers of lipid peroxidation.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Overexpression of glutathione peroxidase increases the resistance of neuronal cells to Abeta-mediated neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Intracellular generation of free radicals and modifications of detoxifying enzymes in cultured neurons from the developing rat forebrain in response to transient hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Folate status, vascular disease and cognition in elderly Canadians.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Nutritional status of free-living Alzheimer's patients

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Further evidence on the effects of vitamin B12 and folate levels on episodic memory functioning: a population-based study of healthy very old adults

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Vitamin B(12) and folate in relation to the development of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

CSF-folate levels are decreased in late-onset AD patients

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Homocysteine, Alzheimer's disease, and cognitive function

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Antioxidant mechanisms in apolipoprotein E deficient mice prior to and following closed head injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Interactions between apolipoprotein E gene and dietary alpha-tocopherol influence cerebral oxidative damage in aged mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

The Swedish APP670/671 Alzheimer's disease mutation: the first evidence for strikingly increased oxidative injury in the temporal inferior cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Amyloid-beta: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

The cerebrocortical areas in normal brain aging and in Alzheimer's disease: noticeable differences in the lipid peroxidation level and in antioxidant defense

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Mechanisms of amyloid beta protein-induced modification in ion transport systems: implications for neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Dietary links to Alzheimer's disease: 1999 update.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Could diet be used to reduce the risk of developing Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

Free radical damage, iron, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901001-8

7 January 2021

10.1016/S0891-5849(02)01001-8

Identifiers

DOI

1 reference

30 November 2017

1 reference