HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics (Q44219231)

30 November 2017

title

HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics (English)

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30 November 2017

3

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30 November 2017

Eric Ennifar

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30 November 2017

Jean-Christophe Paillart

2

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30 November 2017

Bernard Ehresmann

4

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30 November 2017

Chantal Ehresmann

5

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30 November 2017

Philippe Dumas

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30 November 2017

Philippe Walter

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30 November 2017

language of work or name

English

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publication date

14 November 2002

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Journal of Biological Chemistry

30 November 2017

published in

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30 November 2017

volume

278

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30 November 2017

issue

4

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30 November 2017

page(s)

2723-2730

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Strategies in the design of antiviral drugs

30 November 2017

cites work

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A 19-nucleotide sequence upstream of the 5' major splice donor is part of the dimerization domain of human immunodeficiency virus 1 genomic RNA.

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A loop-loop "kissing" complex is the essential part of the dimer linkage of genomic HIV-1 RNA

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The kissing hairpin sequence promotes recombination within the HIV-I 5' leader region.

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Impact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging

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Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site

21 January 2018

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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

21 January 2018

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Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

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The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges

21 January 2018

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Non-canonical interactions in a kissing loop complex: the dimerization initiation site of HIV-1 genomic RNA.

21 January 2018

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RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide

21 January 2018

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Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction.

21 January 2018

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics

21 January 2018

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Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

21 January 2018

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Structural origins of gentamicin antibiotic action

21 January 2018

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Dimer initiation sequence of HIV-1Lai genomic RNA: NMR solution structure of the extended duplex

21 January 2018

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Structure of the dimer initiation complex of HIV-1 genomic RNA

21 January 2018

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Aminoglycoside-RNA interactions

21 January 2018

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Aminoglycoside binding displaces a divalent metal ion in a tRNA-neomycin B complex

21 January 2018

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An antibiotic-binding motif of an RNA fragment derived from the A-site-related region of Escherichia coli 16S rRNA.

21 January 2018

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Footprinting, circular dichroism and UV melting studies on neomycin B binding to the packaging region of human immunodeficiency virus type-1 RNA.

21 January 2018

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Design of novel antibiotics that bind to the ribosomal acyltransfer site

21 January 2018

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Dimerization of HIV-1 genomic RNA of subtypes A and B: RNA loop structure and magnesium binding

21 January 2018

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In vitro evidence for a long range pseudoknot in the 5'-untranslated and matrix coding regions of HIV-1 genomic RNA

21 January 2018

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Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunit

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M205726200

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30 November 2017

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