Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein (Q44253539)

1 December 2017

Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein (English)

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1 December 2017

5

Len Neckers

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1 December 2017

4

Jane Trepel

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1 December 2017

Yun-Jin Jung

1

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1 December 2017

Jennifer S Isaacs

series ordinal

2

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1 December 2017

Sunmin Lee

series ordinal

3

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1 December 2017

language of work or name

English

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publication date

17 December 2002

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Journal of Biological Chemistry

1 December 2017

8

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based on heuristic

inferred from page(s)

published in

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1 December 2017

278

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1 December 2017

7445-7452

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1 December 2017

9

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Enhanced invasion and liver colonization by lung carcinoma cells overexpressing the type 1 insulin-like growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Dynamic instability of microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Physiochemical aspects of tubulin-interacting antimitotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Microtubules and actin filaments: dynamic targets for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Microtubules and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Stimulation of human interleukin 1 production and specific mRNA expression by microtubule-disrupting drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Protein kinase Cdelta-dependent induction of manganese superoxide dismutase gene expression by microtubule-active anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Cytoskeletal control of gene expression: depolymerization of microtubules activates NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Microtubule integrity regulates src-like and extracellular signal-regulated kinase activities in human pro-monocytic cells. Importance for interleukin-1 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Activators and target genes of Rel/NF-kappaB transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

NF-kappaB activation and inhibition: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Multiple signals converging on NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Expression of hypoxia-inducible factor 1? in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

The influence of microtubule integrity on plasma membrane fluidity in L929 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Transfer and amplification of a mutant beta-tubulin gene results in colcemid dependence: use of the transformant to demonstrate regulation of beta-tubulin subunit levels by protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Recent advances in understanding NF-kappaB regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Nuclear transcription factor-kappaB as a target for cancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

Direct observation of microtubule dynamics in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209804200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209804200

1 reference

1 December 2017

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