c-Myc induces cytochrome c release in Rat1 fibroblasts by increasing outer mitochondrial membrane permeability in a Bid-dependent manner (Q44427683)

2 December 2017

title

c-Myc induces cytochrome c release in Rat1 fibroblasts by increasing outer mitochondrial membrane permeability in a Bid-dependent manner (English)

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2 December 2017

1

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2 December 2017

4

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2 December 2017

D Hancock

2

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2 December 2017

G Evan

series ordinal

3

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2 December 2017

publication date

1 May 2003

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Cell Death & Differentiation

2 December 2017

published in

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2 December 2017

volume

10

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2 December 2017

issue

5

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2 December 2017

page(s)

599-608

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The Myc/Max/Mad network and the transcriptional control of cell behavior

2 December 2017

cites work

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

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BCL-2 family members and the mitochondria in apoptosis

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The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation

21 January 2018

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

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Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

21 January 2018

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Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

21 January 2018

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Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

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Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

21 January 2018

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Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

21 January 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

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Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

21 January 2018

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Ras signalling and apoptosis

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

21 January 2018

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Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

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Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

21 January 2018

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The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals

21 January 2018

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

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Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

21 January 2018

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Solution structure of BID, an intracellular amplifier of apoptotic signaling

21 January 2018

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Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

21 January 2018

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Cytochrome c release from mitochondria proceeds by a two-step process

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

The mitochondrion in apoptosis: how Pandora's box opens

21 January 2018

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Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

7 January 2021

Traps to catch unwary oncogenes

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

7 January 2021

A matter of life and cell death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

7 January 2021

Cardiolipin provides specificity for targeting of tBid to mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401211

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401211

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2 December 2017

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