AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability (Q44436375)

3 December 2017

AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability (English)

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3 December 2017

Yu Holly Hong

1

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3 December 2017

Usha S Varanasi

series ordinal

2

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3 December 2017

Wenbo Yang

series ordinal

3

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3 December 2017

Todd Leff

series ordinal

4

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3 December 2017

language of work or name

English

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publication date

9 May 2003

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Journal of Biological Chemistry

3 December 2017

7

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based on heuristic

inferred from page(s)

published in

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3 December 2017

278

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3 December 2017

27495-27501

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3 December 2017

30

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Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences

3 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Diminished insulin and glucagon secretory responses to arginine in nondiabetic subjects with a mutation in the hepatocyte nuclear factor-4alpha/MODY1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Regulation of a transcription factor network required for differentiation and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Mitogen-activated protein kinase regulates transcription of the ApoCIII gene. Involvement of the orphan nuclear receptor HNF4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

cis-acting elements and transcription factors involved in the promoter activity of the human factor VIII gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304112200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304112200

1 reference

3 December 2017

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