Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition (Q44582774)

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scientific article published in September 2003

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English	Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition	scientific article published in September 2003

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scholarly article

1 reference

Europe PubMed Central

4 December 2017

Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition (English)

1 reference

Europe PubMed Central

4 December 2017

author name string

Gudrun Totzke

1

1 reference

Europe PubMed Central

4 December 2017

Klaus Schulze-Osthoff

2

1 reference

Europe PubMed Central

4 December 2017

Reiner U Jänicke

3

1 reference

Europe PubMed Central

4 December 2017

language of work or name

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publication date

1 September 2003

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Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

22

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Europe PubMed Central

4 December 2017

39

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Europe PubMed Central

4 December 2017

8021-8030

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Europe PubMed Central

4 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206837

0 references

Absence of nuclear factor kappaB inhibition by NSAIDs in hepatocytes

1 reference

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Many actions of cyclooxygenase-2 in cellular dynamics and in cancer

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Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity

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The kiss of death: promises and failures of death receptors and ligands in cancer therapy

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Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer.

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Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor

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Cyclooxygenase-2: a novel target for cancer chemotherapy?

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Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

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Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

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The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells

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Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells

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Potential and caveats of TRAIL in cancer therapy

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Lack of cyclooxygenase-2 activity in HT-29 human colorectal carcinoma cells

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The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

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Nuclear c-Myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells

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Cyclin D3 sensitizes tumor cells to tumor necrosis factor-induced, c-Myc-dependent apoptosis

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway

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NF-kappaB at the crossroads of life and death

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Reverse transcriptase-polymerase chain reaction (RT-PCR): a sensitive method to examine basic fibroblast growth factor-induced expression of the early growth response gene-1 (egr-1) in human umbilical arterial endothelial cells

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Cyclooxygenase-2 inducing Mcl-1-dependent survival mechanism in human lung adenocarcinoma CL1.0 cells. Involvement of phosphatidylinositol 3-kinase/Akt pathway

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Cyclooxygenase-2 expression inhibits trophic withdrawal apoptosis in nerve growth factor-differentiated PC12 cells

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21 January 2018

COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells

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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

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Emerging roles of caspase-3 in apoptosis

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Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs

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Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

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Apoptosis signaling by death receptors.

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The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

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Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells

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The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

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Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen

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Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues

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The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

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Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer

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Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

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Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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7 January 2021

based on heuristic

inferred from DOI database lookup

COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

1 reference

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7 January 2021

based on heuristic

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Identification of syntenin and other TNF-inducible genes in human umbilical arterial endothelial cells by suppression subtractive hybridization

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based on heuristic

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Cyclooxygenase-2 inhibitors in tumorigenesis (Part II)

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1206837

1 reference

Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

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